Defects in the origin licensing checkpoint stresses cells exiting G0

J. Julian Blow (Lead / Corresponding author)

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    The full licensing of replication origins in late G1 is normally enforced by the licensing checkpoint. In this issue, Matson et al. (2019. J. Cell Biol. show that this checkpoint is inoperative in cells exiting from G0, resulting in incomplete origin licensing and consequent replicative stress.

    Original languageEnglish
    Pages (from-to)2080-2081
    Number of pages2
    JournalJournal of Cell Biology
    Issue number7
    Early online date11 Jun 2019
    Publication statusPublished - 1 Jul 2019


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