Dependency rather than old age increases the risk of warfarin-related bleeding

Barclay M. Goudie, Peter T. Donnan, Geraldine Fairfield, Sally S. Al-Agilly, Philip G. Cachia

    Research output: Contribution to journalArticlepeer-review

    19 Citations (Scopus)

    Abstract

    There is uncertainty about the safety of anticoagulation with warfarin in the elderly. This cohort study investigated the risk factors for warfarin-related bleeding in a primary care setting. In multiple regression analyses increased risk of bleeding was associated with domiciliary monitoring of international normalised ratio (INR), low proportion of INR tests in the target range, high intensity of anticoagulation, and male sex. Age was not associated with increased risk after adjustment. High levels of dependency, not old age, should raise concerns about the safety of anticoagulation with warfarin.

    Original languageEnglish
    Pages (from-to)690-692
    Number of pages3
    JournalBritish Journal of General Practice
    Volume54
    Issue number506
    Publication statusPublished - 1 Sep 2004

    Keywords

    • Aged
    • Anticoagulants
    • Dependency
    • Haemorrhage
    • Risk
    • Warfarin

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