Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites

Keyphrases

• Melamine 100%
• Trypanosomatid Parasites 100%
• Nitroheterocycles 100%
• Human African Trypanosomiasis 66%
• Trypanosoma Cruzi (T. cruzi) 66%
• Purine nucleosides 66%
• Growth Inhibition 33%
• Rhodesiense 33%
• Leishmania Donovani 33%
• Drug Use 33%
• Auxotroph 33%
• T. Brucei 33%
• In Vitro Activity 33%
• Melarsoprol 33%
• P2 Transporter 33%
• Melamine Derivatives 33%
• Trypanosoma Brucei 33%
• Trypanosomatids 33%
• Nucleoside Transporters 33%
• Trypanocidal Activity 33%
• Inhibitory Concentration 33%
• Purine 33%
• Human Host 33%
• Rodent Models 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Trypanosomatidae 100%
• Melamine 100%
• African Trypanosomiasis 66%
• Leishmania donovani 33%
• Infectious Agent 33%
• Trypanosoma Brucei Brucei 33%
• Melarsoprol 33%
• Trypanosoma Cruzi 33%
• Purine Derivative 33%
• Nucleic Acid Base 33%
• Nucleoside Transporter 33%
• Purine Nucleoside 33%
• Purine 33%