Determinants of the substrate specificity of human cytochrome P-450 CYP2D6: design and construction of a mutant with testosterone hydroxylase activity

Gillian Smith, Sandeep Modi, Ilona Pillai, Lu-Yun Lian, Michael J. Sutcliffe, Michael P. Pritchard, Thomas Friedberg, Gordon C. K. Roberts, C. Roland Wolf

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    Biochemistry, Genetics and Molecular Biology