Development of a guideline for orthopaedic management in the care of children and young people with Duchenne muscular dystrophy in the UK National Health Service

TY - JOUR

T1 - Development of a guideline for orthopaedic management in the care of children and young people with Duchenne muscular dystrophy in the UK National Health Service

AU - Henman, Philip D

AU - Turner, Catherine

AU - Aird, James

AU - Atherton, William Guy

AU - Campbell, Donald

AU - Carpenter, Clare

AU - Carsi, Maria Belen

AU - Dixon, Melville

AU - Giannakakis, Nikolaos

AU - Girdler-Hardy, Thomas

AU - Hulme, Alison

AU - James, Meredith

AU - Joseph, Shuko

AU - Kiely, Nigel T

AU - Ohly, Kirsty

AU - Porter, Anna

AU - Rad, Darius

AU - Reuben, Emily

AU - Walton, Roger

AU - Wong, Sze Choong

AU - Guglieri, Michela

N1 - © The Author(s) 2025.

PY - 2025/8

Y1 - 2025/8

N2 - People living with the rare, genetic condition Duchenne muscular dystrophy have particular orthopaedic care needs that are not universally understood or implemented at sites across the UK, putting them at risk of not receiving the correct treatment. They may require orthopaedic management and intervention for contractures caused by their muscle weakness. Importantly, they are also at a high risk of fractures due to increased bone fragility as part of the nature of Duchenne muscular dystrophy but also resulting from reduced weight-bearing and from the long-term use of corticosteroids as standard of care. In addition, progressive skeletal muscle weakness increases the risk of falls that may cause fractures. DMD Care UK's orthopaedic working group has developed a guideline by consensus to inform all those involved in the orthopaedic management of people with Duchenne muscular dystrophy about the care needs and imperatives. This covers children and adults and focuses on fracture management and elective orthopaedic procedures. The guideline has been endorsed by the British Society for Children's Orthopaedic Surgery.

AB - People living with the rare, genetic condition Duchenne muscular dystrophy have particular orthopaedic care needs that are not universally understood or implemented at sites across the UK, putting them at risk of not receiving the correct treatment. They may require orthopaedic management and intervention for contractures caused by their muscle weakness. Importantly, they are also at a high risk of fractures due to increased bone fragility as part of the nature of Duchenne muscular dystrophy but also resulting from reduced weight-bearing and from the long-term use of corticosteroids as standard of care. In addition, progressive skeletal muscle weakness increases the risk of falls that may cause fractures. DMD Care UK's orthopaedic working group has developed a guideline by consensus to inform all those involved in the orthopaedic management of people with Duchenne muscular dystrophy about the care needs and imperatives. This covers children and adults and focuses on fracture management and elective orthopaedic procedures. The guideline has been endorsed by the British Society for Children's Orthopaedic Surgery.

KW - Duchenne muscular dystrophy

KW - guidelines

KW - fracture management

KW - elective surgery

U2 - 10.1177/18632521251348972

DO - 10.1177/18632521251348972

M3 - Article

C2 - 40575436

SN - 1863-2521

VL - 19

SP - 267

EP - 275

JO - Journal of children's orthopaedics

JF - Journal of children's orthopaedics

IS - 4

ER -