Diagnostic tools in male infertility

C L Barratt (Lead / Corresponding author), Justin C. St John

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)


This review critically analyses the diagnostic value of conventional semen analysis and sperm function testing. It is clear from the data available that a high quality comprehensive semen assessment is a basic requirement in the diagnosis of the infertile couple. Sperm function testing has given disappointing results and a new generation of sperm function tests is required, which are cost effective, reliable and provide clinically significant information. In the future there will be an increasing use of molecular techniques to diagnose male infertility. Specific attention is given to the role of polymerase chain reaction in the diagnosis of genital infection and Y chromosomal and mitochondrial DNA deletions as examples.

Original languageEnglish
Pages (from-to)51-61
Number of pages11
JournalHuman Reproduction
Volume13 Suppl 1
Publication statusPublished - Apr 1998


  • Biopsy
  • Humans
  • Infertility, Male/diagnosis
  • Male
  • Molecular Biology/methods
  • Semen/physiology
  • Spermatozoa/physiology
  • Testis/pathology


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