Abstract
Any established or aspiring model organism must justify itself using two criteria: does the model organism offer experimental advantages not offered by competing systems? And will any discoveries made using the model be of wider relevance? This review addresses these issues for the social amoeba Dictyostelium and highlights some of the organisms more recent applications. These cover a remarkably wide gamut, ranging from sociobiological to medical research with much else in between.
Original language | English |
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Pages (from-to) | 717-726 |
Number of pages | 10 |
Journal | Genetics |
Volume | 185 |
Issue number | 3 |
DOIs | |
Publication status | Published - Jul 2010 |
Keywords
- Host-pathogen interactions
- Heavy-chain gene
- Transcription factor
- Social ameba
- Legionella-pneumophila
- Pseudomonas aeruginosa
- Normal morphogenesis
- Molecular phylogeny
- Cheater mutants
- Wild type