Dictyostelium finds new roles to model

Jeffrey G. Williams

    Research output: Contribution to journalReview article

    60 Citations (Scopus)

    Abstract

    Any established or aspiring model organism must justify itself using two criteria: does the model organism offer experimental advantages not offered by competing systems? And will any discoveries made using the model be of wider relevance? This review addresses these issues for the social amoeba Dictyostelium and highlights some of the organisms more recent applications. These cover a remarkably wide gamut, ranging from sociobiological to medical research with much else in between.

    Original languageEnglish
    Pages (from-to)717-726
    Number of pages10
    JournalGenetics
    Volume185
    Issue number3
    DOIs
    Publication statusPublished - Jul 2010

    Keywords

    • Host-pathogen interactions
    • Heavy-chain gene
    • Transcription factor
    • Social ameba
    • Legionella-pneumophila
    • Pseudomonas aeruginosa
    • Normal morphogenesis
    • Molecular phylogeny
    • Cheater mutants
    • Wild type

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