Abstract
Allergic asthma is characterised by the presence of circulating specific immunoglobulin E (IgE) or a positive skin prick test (SPT) to a common aeroallergen. Type-2 inflammatory (T2) cytokines stimulate IgE synthesis in response to aeroallergen, resulting in chronic eosinophilic airway mucosal inflammation.
Original language | English |
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Article number | 1802102 |
Journal | European Respiratory Journal |
Volume | 53 |
Issue number | 6 |
Early online date | 17 Mar 2019 |
DOIs | |
Publication status | Published - 13 Jun 2019 |
Keywords
- asthma
- asthma control
- type-2 inflammation
- Spirometry
- impulse oscillometry
- allergic asthma
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
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Lipworth, Brian
- Respiratory Medicine and Gastroenterology - Clinical Professor (Teaching and Research) of Allergy and Respiratory Medicine
Person: Academic