Differences in lung bioavailability between different propellants for fluticasone propionate

Andrew M. Wilson, Erika J. Sims, Linda C. Orr, Brian J. Lipworth

    Research output: Contribution to journalLetterpeer-review

    20 Citations (Scopus)

    Abstract

    The lung bioavailability (as adrenal suppression) of fluticasone propionate was about twofold greater with chlorofluorocarbons than hydrofluoroalkane as propellant. Direct switching between formulations on a microg equivalent may therefore be inadvisable.
    Original languageEnglish
    Pages (from-to)1357-8
    Number of pages2
    JournalLancet
    Volume354
    Issue number9187
    DOIs
    Publication statusPublished - 16 Oct 1999

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