Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction: A GoDARTS Mendelian Randomization Study and Meta-Analysis

Ify R. Mordi; Ewan R. Pearson; Colin N. A. Palmer; Alexander S. F. Doney; Chim C. Lang

doi:10.1161/CIRCULATIONAHA.118.038602

Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction: A GoDARTS Mendelian Randomization Study and Meta-Analysis

Ify R. Mordi (Lead / Corresponding author), Ewan R. Pearson, Colin N. A. Palmer, Alexander S. F. Doney, Chim C. Lang

Research output: Contribution to journal › Letter › peer-review

6 Citations (Scopus)

67 Downloads (Pure)

Original language	English
Pages (from-to)	986-988
Number of pages	3
Journal	Circulation
Volume	139
Issue number	7
Early online date	11 Feb 2019
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.118.038602
Publication status	Published - 12 Feb 2019

Keywords

Mendelian randomization analysis
coronary artery disease
genetics
heart failure

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

Access to Document

10.1161/CIRCULATIONAHA.118.038602

Author Accepted ManuscriptAccepted author manuscript, 438 KB

Cite this

Mordi, I. R., Pearson, E. R., Palmer, C. N. A., Doney, A. S. F., & Lang, C. C. (2019). Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction: A GoDARTS Mendelian Randomization Study and Meta-Analysis. Circulation, 139(7), 986-988. https://doi.org/10.1161/CIRCULATIONAHA.118.038602

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title = "Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction: A GoDARTS Mendelian Randomization Study and Meta-Analysis",

keywords = "Mendelian randomization analysis, coronary artery disease, genetics, heart failure",

author = "Mordi, {Ify R.} and Pearson, {Ewan R.} and Palmer, {Colin N. A.} and Doney, {Alexander S. F.} and Lang, {Chim C.}",

note = "IM is supported by National Health Service Education for Scotland/Chief Scientist Office Postdoctoral Clinical Lectureship (PCL 17/07). The Go-DARTS study was supported by the following: genotyping was facilitated by capital funding from the Scottish Government Chief Scientist Office Generation Scotland initiative (www.generationscotland.org); The Wellcome Trust U.K. type 2 diabetes case control collection (GoDARTS2) was funded by a Wellcome Trust [grant number GR02960] and the GWAS genotyping was performed as part of the Wellcome Trust Case Control Consortium 2 [084726/Z/08/Z, 085475/Z/08/Z, 085475/B/08/Z].",

year = "2019",

month = feb,

day = "12",

doi = "10.1161/CIRCULATIONAHA.118.038602",

language = "English",

volume = "139",

pages = "986--988",

journal = "Circulation",

issn = "0009-7322",

publisher = "American Heart Association",

number = "7",

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Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction: A GoDARTS Mendelian Randomization Study and Meta-Analysis. / Mordi, Ify R. (Lead / Corresponding author); Pearson, Ewan R.; Palmer, Colin N. A. et al.
In: Circulation, Vol. 139, No. 7, 12.02.2019, p. 986-988.

Research output: Contribution to journal › Letter › peer-review

TY - JOUR

T1 - Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction

T2 - A GoDARTS Mendelian Randomization Study and Meta-Analysis

AU - Mordi, Ify R.

AU - Pearson, Ewan R.

AU - Palmer, Colin N. A.

AU - Doney, Alexander S. F.

AU - Lang, Chim C.

N1 - IM is supported by National Health Service Education for Scotland/Chief Scientist Office Postdoctoral Clinical Lectureship (PCL 17/07). The Go-DARTS study was supported by the following: genotyping was facilitated by capital funding from the Scottish Government Chief Scientist Office Generation Scotland initiative (www.generationscotland.org); The Wellcome Trust U.K. type 2 diabetes case control collection (GoDARTS2) was funded by a Wellcome Trust [grant number GR02960] and the GWAS genotyping was performed as part of the Wellcome Trust Case Control Consortium 2 [084726/Z/08/Z, 085475/Z/08/Z, 085475/B/08/Z].

PY - 2019/2/12

Y1 - 2019/2/12

KW - Mendelian randomization analysis

KW - coronary artery disease

KW - genetics

KW - heart failure

UR - http://www.scopus.com/inward/record.url?scp=85061380856&partnerID=8YFLogxK

U2 - 10.1161/CIRCULATIONAHA.118.038602

DO - 10.1161/CIRCULATIONAHA.118.038602

M3 - Letter

C2 - 30742529

SN - 0009-7322

VL - 139

SP - 986

EP - 988

JO - Circulation

JF - Circulation

IS - 7

ER -

Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction: A GoDARTS Mendelian Randomization Study and Meta-Analysis

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Identifying Novel Opportunities for Translational Research, Precision Medicine and Drug Repurposing in Cardiovascular Disease using Pharmacoepidemiology, Genetic Epidemiology and Bioinformatics

Lang, Chim

Mordi, Ify

Cite this

Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction: A GoDARTS Mendelian Randomization Study and Meta-Analysis

Keywords

ASJC Scopus subject areas

Access to Document

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Projects

Identifying Novel Opportunities for Translational Research, Precision Medicine and Drug Repurposing in Cardiovascular Disease using Pharmacoepidemiology, Genetic Epidemiology and Bioinformatics

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Lang, Chim

Mordi, Ify

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