Abstract
Evidence of long-term beneficial effects of ß-blockers on mortality and morbidity in patients with heart failure has been demonstrated in recent randomized trials. However, not all ß-blockers are identical. Carvedilol, a nonselective ß- and a-adrenergic blocker, can potentially blunt the release of noradrenaline by blocking presynaptic ß2-adrenergic receptors. To test this hypothesis, we have compared the effects of carvedilol and atenolol on plasma noradrenaline during exercise in healthy young volunteers.
Original language | English |
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Pages (from-to) | 134-138 |
Number of pages | 5 |
Journal | British Journal of Clinical Pharmacology |
Volume | 55 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2003 |