Difficulties arising in reimbursement recommendations on new medicines due to inadequate reporting of population adjustment indirect comparison method

Eileen Holmes (Lead / Corresponding author), Joy Leahy, Cathal D. Walsh, Arthur White, Peter T. Donnan, Felicity Lamrock

Research output: Contribution to journalArticle

2 Citations (Scopus)
3 Downloads (Pure)

Abstract

Indirect treatment comparisons are useful to estimate relative treatment effects when head‐to‐head studies are not conducted. Statisticians at the National Centre for Pharmacoeconomics Ireland (NCPE) and Scottish Medicines Consortium (SMC) assess the clinical and cost effectiveness of new medicines as part of multidisciplinary teams. We describe some shared observations on areas where reporting of population‐adjustment indirect comparison methods are causing uncertainty in our recommendations to decision making committees when assessing reimbursement of medicines.
Original languageEnglish
JournalResearch Synthesis Methods
Early online date27 Jun 2019
DOIs
Publication statusE-pub ahead of print - 27 Jun 2019

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