Difficulties arising in reimbursement recommendations on new medicines due to inadequate reporting of population adjustment indirect comparison methods

Eileen Holmes; Joy Leahy; Cathal D. Walsh; Arthur White; Peter T. Donnan; Felicity Lamrock

doi:10.1002/jrsm.1368

Difficulties arising in reimbursement recommendations on new medicines due to inadequate reporting of population adjustment indirect comparison methods

Eileen Holmes (Lead / Corresponding author), Joy Leahy, Cathal D. Walsh, Arthur White, Peter T. Donnan, Felicity Lamrock

Population Health and Genomics

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5 Citations (Scopus)

278 Downloads (Pure)

Abstract

Indirect treatment comparisons are useful to estimate relative treatment effects when head-to-head studies are not conducted. Statisticians at the National Centre for Pharmacoeconomics Ireland (NCPE) and Scottish Medicines Consortium (SMC) assess the clinical and cost-effectiveness of new medicines as part of multidisciplinary teams. We describe some shared observations on areas where reporting of population-adjustment indirect comparison methods is causing uncertainty in our recommendations to decision-making committees when assessing reimbursement of medicines.

Original language	English
Pages (from-to)	615-617
Number of pages	3
Journal	Research Synthesis Methods
Volume	10
Issue number	4
Early online date	27 Jun 2019
DOIs	https://doi.org/10.1002/jrsm.1368
Publication status	Published - Dec 2019

Keywords

decision making
evidence synthesis
population-adjusted indirect comparisons
statistical models

ASJC Scopus subject areas

Education

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10.1002/jrsm.1368

Author Accepted ManuscriptAccepted author manuscript, 1.11 MB

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Difficulties arising in reimbursement recommendations on new medicines due to inadequate reporting of population adjustment indirect comparison methods. / Holmes, Eileen (Lead / Corresponding author); Leahy, Joy; Walsh, Cathal D. et al.
In: Research Synthesis Methods, Vol. 10, No. 4, 12.2019, p. 615-617.

Research output: Contribution to journal › Article › peer-review

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Difficulties arising in reimbursement recommendations on new medicines due to inadequate reporting of population adjustment indirect comparison methods

Abstract

Keywords

ASJC Scopus subject areas

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