Diffusible signal factor-dependent cell-cell signaling and virulence in the nosocomial pathogen Stenotrophomonas maltophilia

Yvonne Fouhy, Karl Scanlon, Katherine Schouest, Charles Spillane, Lisa Crossman, Matthew B. Avison, Robert P. Ryan, J. Maxwell Dow

    Research output: Contribution to journalArticlepeer-review

    112 Citations (Scopus)

    Abstract

    The genome of Stenotrophomonas maltophilia encodes a cell-cell signaling system that is highly related to the diffusible signal factor (DSF)-dependent system of the phytopathogen Xanthomonas campestris. Here we show that in S. maltophilia, DSF signaling controls factors contributing to the virulence and antibiotic resistance of this important nosocomial pathogen.
    Original languageEnglish
    Pages (from-to)4964-4968
    Number of pages5
    JournalJournal of Bacteriology
    Volume189
    Issue number13
    DOIs
    Publication statusPublished - 2007

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