Keyphrases
E3 Ligase
100%
Von Hippel-Lindau
100%
Small Molecule Ligands
100%
Proteolysis Targeting chimera (PROTAC)
100%
Degrader
100%
Ubiquitination
40%
Ubiquitin-proteasome System
40%
Non-native
20%
Substrate Proteins
20%
Ligand Binding
20%
Proteasomal Degradation
20%
Structure-based Design
20%
Essential Enzymes
20%
Hypoxia-inducible Factor
20%
Binding Affinity
20%
New Ligand
20%
Rationally Designed
20%
Cullin-RING E3 Ligase
20%
Field Development
20%
Bifunctional Molecules
20%
Targeted Protein Degradation
20%
E3 Ligase Ligands
20%
Stumbling
20%
Biochemistry, Genetics and Molecular Biology
Small Molecule
100%
Protein Catabolism
100%
Ligase
100%
Ubiquitination
33%
Proteasome
33%
Ubiquitin
33%
Enzyme
16%
Binding Affinity
16%
Ligand Binding
16%
Cullin
16%
Hypoxia-Inducible Factors
16%
Pharmacology, Toxicology and Pharmaceutical Science
Ligase
100%
Ubiquitin
33%
Proteasome
33%
Hypoxia Inducible Factor
16%
Cullin
16%