Discovery of small molecule ligands for the von Hippel-Lindau (VHL) E3 ligase and their use as inhibitors and PROTAC degraders

Claudia J. Diehl, Alessio Ciulli (Lead / Corresponding author)

Research output: Contribution to journal › Review article › peer-review

94 Citations (Scopus)

258 Downloads (Pure)

5 results

Finished
PROTACT Linker Design: towards Functionality (PREDICT)
Ciulli, A. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/05/21 → 30/06/23
Project: Research
DrugE3CRL's: Probing Druggability of Multisubunit Complexes: E3 Cullin RING Ligases (ERC Starting Grant)
Ciulli, A. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/05/13 → 30/04/18
Project: Research
A Systems Approach for the Fragment-based Development of Selective Chemical Probes of Bromodomain Function (joint with University of Oxford)
Ciulli, A. (Investigator)
Biotechnology and Biological Sciences Research Council
8/04/13 → 7/06/15
Project: Research
Dissecting and Exploiting Molecular Recognition at Protein-Protein Interfaces (David Phillips Fellowship)
Ciulli, A. (Investigator)
Biotechnology and Biological Sciences Research Council
8/04/13 → 7/07/15
Project: Research
Design of Orthogonal Molecular Probes Targeting Engineered Von-Hippel Lindau (VHL) E3 Ubiquitin Ligase for the Control of Intercellular Protein Levels
Ciulli, A. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
8/04/13 → 7/04/15
Project: Research