Disinfection of needleless connectors to reduce Staphylococcus aureus bacterial load

Patrícia Kuerten Rocha, Claire M Rickard, Ana Cristina Gales, Thaís Cristine Marques Sincero, Gillian Ray-Barruel, Amanda J Ullman, Camila Biazus Dalcin, Mavilde L Gonçalves Pedreira

Research output: Contribution to journalArticlepeer-review

Abstract

HIGHLIGHTS: Compare effectiveness of chemical disinfectants in reducing S. aureus. Five disinfectants reduced the bacterial load, especially chlorhexidine solutions. Focus on Brazilian clinical practice of needleless connector disinfection.

PURPOSE: This study aimed to gain further knowledge about the comparative effectiveness of chemical disinfectants in reducing the bacterial load of NCs inoculated with S. aureus.

METHODS: Disinfection of needleless connectors was undertaken in vitro against S. aureus comparing 70% isopropyl alcohol (IPA), 70% ethanol, 0.5% and 2% chlorhexidine in 70% IPA applied with gauze, and 70% IPA single-use cap (Site-Scrub®).

RESULTS: All disinfectants reduced the bacterial load ( P<0.001), especially the chlorhexidine solutions. Mechanical friction should follow guidelines.

CONCLUSION: This study found that all tested disinfectants effectively reduced the bacterial load and more clinical studies must be developed with a focus on the Brazilian clinical practice of needleless connector disinfection.

Original languageEnglish
Pages (from-to)S26-S31
JournalBritish Journal of Nursing
Volume31
Issue number19
DOIs
Publication statusPublished - 27 Oct 2022

Keywords

  • Humans
  • Disinfection
  • Staphylococcus aureus
  • Chlorhexidine
  • Equipment Contamination/prevention & control
  • Bacterial Load
  • Disinfectants/pharmacology
  • 2-Propanol/pharmacology
  • Ethanol
  • Vascular access device
  • Needleless connector
  • Catheter-related bloodstream infection

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