Disinfection of needleless connectors to reduce Staphylococcus aureus bacterial load

Patrícia Kuerten Rocha; Claire M. Rickard; Ana Cristina Gales; Thaís Cristine Marques Sincero; Gillian Ray-Barruel; Amanda J. Ullman; Camila Biazus Dalcin; Mavilde L. Gonçalves Pedreira

doi:10.12968/bjon.2022.31.19.S26

Disinfection of needleless connectors to reduce Staphylococcus aureus bacterial load

Patrícia Kuerten Rocha (Lead / Corresponding author)
, Claire M. Rickard
, Ana Cristina Gales
, Thaís Cristine Marques Sincero
, Gillian Ray-Barruel
, Amanda J. Ullman
, Camila Biazus Dalcin
, Mavilde L. Gonçalves Pedreira

Health Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Purpose: This study aimed to gain further knowledge about the comparative effectiveness of chemical disinfectants in reducing the bacterial load of NCs inoculated with S. aureus.

Methods: Disinfection of needleless connectors was undertaken in vitro against S. aureus comparing 70% isopropyl alcohol (IPA), 70% ethanol, 0.5% and 2% chlorhexidine in 70% IPA applied with gauze, and 70% IPA single-use cap (Site-Scrub®).

Results: All disinfectants reduced the bacterial load ( P<0.001), especially the chlorhexidine solutions. Mechanical friction should follow guidelines.

Conclusion: This study found that all tested disinfectants effectively reduced the bacterial load and more clinical studies must be developed with a focus on the Brazilian clinical practice of needleless connector disinfection.

Original language	English
Pages (from-to)	S26-S31
Journal	British Journal of Nursing
Volume	31
Issue number	19
DOIs	https://doi.org/10.12968/bjon.2022.31.19.S26
Publication status	Published - 27 Oct 2022

Keywords

Humans
Disinfection
Staphylococcus aureus
Chlorhexidine
Equipment Contamination/prevention & control
Bacterial Load
Disinfectants/pharmacology
2-Propanol/pharmacology
Ethanol
Vascular access device
Needleless connector
Catheter-related bloodstream infection

ASJC Scopus subject areas

General Nursing

Access to Document

10.12968/bjon.2022.31.19.S26

Cite this

@article{86dc3390025c4d918f359bec2390d1b5,

title = "Disinfection of needleless connectors to reduce Staphylococcus aureus bacterial load",

abstract = "Purpose: This study aimed to gain further knowledge about the comparative effectiveness of chemical disinfectants in reducing the bacterial load of NCs inoculated with S. aureus.Methods: Disinfection of needleless connectors was undertaken in vitro against S. aureus comparing 70\% isopropyl alcohol (IPA), 70\% ethanol, 0.5\% and 2\% chlorhexidine in 70\% IPA applied with gauze, and 70\% IPA single-use cap (Site-Scrub{\textregistered}).Results: All disinfectants reduced the bacterial load ( P<0.001), especially the chlorhexidine solutions. Mechanical friction should follow guidelines. Conclusion: This study found that all tested disinfectants effectively reduced the bacterial load and more clinical studies must be developed with a focus on the Brazilian clinical practice of needleless connector disinfection.",

keywords = "Humans, Disinfection, Staphylococcus aureus, Chlorhexidine, Equipment Contamination/prevention \& control, Bacterial Load, Disinfectants/pharmacology, 2-Propanol/pharmacology, Ethanol, Vascular access device, Needleless connector, Catheter-related bloodstream infection",

author = "Rocha, \{Patr{\'i}cia Kuerten\} and Rickard, \{Claire M.\} and Gales, \{Ana Cristina\} and Sincero, \{Tha{\'i}s Cristine Marques\} and Gillian Ray-Barruel and Ullman, \{Amanda J.\} and Dalcin, \{Camila Biazus\} and Pedreira, \{Mavilde L. Gon{\c c}alves\}",

year = "2022",

month = oct,

day = "27",

doi = "10.12968/bjon.2022.31.19.S26",

language = "English",

volume = "31",

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journal = "British Journal of Nursing",

issn = "0966-0461",

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}

TY - JOUR

T1 - Disinfection of needleless connectors to reduce Staphylococcus aureus bacterial load

AU - Rocha, Patrícia Kuerten

AU - Rickard, Claire M.

AU - Gales, Ana Cristina

AU - Sincero, Thaís Cristine Marques

AU - Ray-Barruel, Gillian

AU - Ullman, Amanda J.

AU - Dalcin, Camila Biazus

AU - Pedreira, Mavilde L. Gonçalves

PY - 2022/10/27

Y1 - 2022/10/27

N2 - Purpose: This study aimed to gain further knowledge about the comparative effectiveness of chemical disinfectants in reducing the bacterial load of NCs inoculated with S. aureus.Methods: Disinfection of needleless connectors was undertaken in vitro against S. aureus comparing 70% isopropyl alcohol (IPA), 70% ethanol, 0.5% and 2% chlorhexidine in 70% IPA applied with gauze, and 70% IPA single-use cap (Site-Scrub®).Results: All disinfectants reduced the bacterial load ( P<0.001), especially the chlorhexidine solutions. Mechanical friction should follow guidelines. Conclusion: This study found that all tested disinfectants effectively reduced the bacterial load and more clinical studies must be developed with a focus on the Brazilian clinical practice of needleless connector disinfection.

AB - Purpose: This study aimed to gain further knowledge about the comparative effectiveness of chemical disinfectants in reducing the bacterial load of NCs inoculated with S. aureus.Methods: Disinfection of needleless connectors was undertaken in vitro against S. aureus comparing 70% isopropyl alcohol (IPA), 70% ethanol, 0.5% and 2% chlorhexidine in 70% IPA applied with gauze, and 70% IPA single-use cap (Site-Scrub®).Results: All disinfectants reduced the bacterial load ( P<0.001), especially the chlorhexidine solutions. Mechanical friction should follow guidelines. Conclusion: This study found that all tested disinfectants effectively reduced the bacterial load and more clinical studies must be developed with a focus on the Brazilian clinical practice of needleless connector disinfection.

KW - Humans

KW - Disinfection

KW - Staphylococcus aureus

KW - Chlorhexidine

KW - Equipment Contamination/prevention & control

KW - Bacterial Load

KW - Disinfectants/pharmacology

KW - 2-Propanol/pharmacology

KW - Ethanol

KW - Vascular access device

KW - Needleless connector

KW - Catheter-related bloodstream infection

U2 - 10.12968/bjon.2022.31.19.S26

DO - 10.12968/bjon.2022.31.19.S26

M3 - Article

C2 - 36306235

SN - 0966-0461

VL - 31

SP - S26-S31

JO - British Journal of Nursing

JF - British Journal of Nursing

IS - 19

ER -

Disinfection of needleless connectors to reduce Staphylococcus aureus bacterial load

Abstract

Keywords

ASJC Scopus subject areas

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