Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis

Atul Kumar, Jacob D. Aguirre, Tara E. C. Condos, R. Julio Martinez-Torres, Viduth K. Chaugule, Rachel Toth, Ramasubramanian Sundaramoorthy, Pascal Mercier, Axel Knebel, Donald E. Spratt, Kathryn R. Barber, Gary S. Shaw (Lead / Corresponding author), Helen Walden (Lead / Corresponding author)

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155 Citations (Scopus)
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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science