Abstract
Ubiquitin is known to accumulate at the sites of DNA damage. The identification of a new ubiquitin ligase, RIDDLIN, provides evidence for a ubiquitin-signalling cascade that regulates the assembly of an important DNA repair complex at a DNA double-strand break.
Original language | English |
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Pages (from-to) | R331-R333 |
Number of pages | 3 |
Journal | Current Biology |
Volume | 19 |
Issue number | 8 |
DOIs | |
Publication status | Published - 28 Apr 2009 |
Keywords
- DAMAGE RESPONSE
- BRCA1
- TARGETS
- CHROMATIN
- PROTEINS
- LIGASE
- SITES
- 53BP1
- FORM