DNA Repair: A RIDDLE at a Double-Strand Break

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    Abstract

    Ubiquitin is known to accumulate at the sites of DNA damage. The identification of a new ubiquitin ligase, RIDDLIN, provides evidence for a ubiquitin-signalling cascade that regulates the assembly of an important DNA repair complex at a DNA double-strand break.

    Original languageEnglish
    Pages (from-to)R331-R333
    Number of pages3
    JournalCurrent Biology
    Volume19
    Issue number8
    DOIs
    Publication statusPublished - 28 Apr 2009

    Keywords

    • DAMAGE RESPONSE
    • BRCA1
    • TARGETS
    • CHROMATIN
    • PROTEINS
    • LIGASE
    • SITES
    • 53BP1
    • FORM

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