DNA Repair: A RIDDLE at a Double-Strand Break

Kevin Hiom

doi:10.1016/j.cub.2009.03.024

DNA Repair: A RIDDLE at a Double-Strand Break

Kevin Hiom

Research output: Contribution to journal › Editorial › peer-review

6 Citations (Scopus)

Abstract

Ubiquitin is known to accumulate at the sites of DNA damage. The identification of a new ubiquitin ligase, RIDDLIN, provides evidence for a ubiquitin-signalling cascade that regulates the assembly of an important DNA repair complex at a DNA double-strand break.

Original language	English
Pages (from-to)	R331-R333
Number of pages	3
Journal	Current Biology
Volume	19
Issue number	8
DOIs	https://doi.org/10.1016/j.cub.2009.03.024
Publication status	Published - 28 Apr 2009

Keywords

DAMAGE RESPONSE
BRCA1
TARGETS
CHROMATIN
PROTEINS
LIGASE
SITES
53BP1
FORM

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10.1016/j.cub.2009.03.024

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title = "DNA Repair: A RIDDLE at a Double-Strand Break",

abstract = "Ubiquitin is known to accumulate at the sites of DNA damage. The identification of a new ubiquitin ligase, RIDDLIN, provides evidence for a ubiquitin-signalling cascade that regulates the assembly of an important DNA repair complex at a DNA double-strand break.",

keywords = "DAMAGE RESPONSE, BRCA1, TARGETS, CHROMATIN, PROTEINS, LIGASE, SITES, 53BP1, FORM",

author = "Kevin Hiom",

year = "2009",

month = apr,

day = "28",

doi = "10.1016/j.cub.2009.03.024",

language = "English",

volume = "19",

pages = "R331--R333",

journal = "Current Biology",

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publisher = "Cell Press",

number = "8",

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TY - JOUR

T1 - DNA Repair

T2 - A RIDDLE at a Double-Strand Break

AU - Hiom, Kevin

PY - 2009/4/28

Y1 - 2009/4/28

N2 - Ubiquitin is known to accumulate at the sites of DNA damage. The identification of a new ubiquitin ligase, RIDDLIN, provides evidence for a ubiquitin-signalling cascade that regulates the assembly of an important DNA repair complex at a DNA double-strand break.

AB - Ubiquitin is known to accumulate at the sites of DNA damage. The identification of a new ubiquitin ligase, RIDDLIN, provides evidence for a ubiquitin-signalling cascade that regulates the assembly of an important DNA repair complex at a DNA double-strand break.

KW - DAMAGE RESPONSE

KW - BRCA1

KW - TARGETS

KW - CHROMATIN

KW - PROTEINS

KW - LIGASE

KW - SITES

KW - 53BP1

KW - FORM

U2 - 10.1016/j.cub.2009.03.024

DO - 10.1016/j.cub.2009.03.024

M3 - Editorial

C2 - 19409282

SN - 0960-9822

VL - 19

SP - R331-R333

JO - Current Biology

JF - Current Biology

IS - 8

ER -

DNA Repair: A RIDDLE at a Double-Strand Break

Abstract

Keywords

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