DUB be good to me

Xingui Liu, Alessio Ciulli (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Induced proximity is reshaping drug discovery. A new study debuts deubiquitinase-targeting chimeras (DUBTACs), small bifunctional molecules that co-opt a deubiquitinase to stabilize a target protein.
Original languageEnglish
Pages (from-to)358-359
Number of pages2
JournalNature Chemical Biology
Volume18
Early online date24 Feb 2022
DOIs
Publication statusPublished - Apr 2022

Keywords

  • Chemical tools
  • Post-translational modifications
  • Small molecules

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