Dupilumab in Chronic Actinic Dermatitis: a retrospective case series

Marese O'Reilly (Lead / Corresponding author), Alexandra Paolino, Pirunthan Pathmarajah, John Ferguson, Catherine H. Smith, Robert Sarkany, Robert Dawe, Andrew Pink, Hiva Fassihi, Sally Ibbotson

Research output: Contribution to journalLetterpeer-review


We report a retrospective case series from two UK photobiology units of twelve patients with concomitant Atopic Dermatitis and Chronic Actinic Dermatitis treated with dupilumab as a systemic monotherapy. Whilst dupilumab is an effective therapy for moderate-severe AD, our results suggest that it may be less effective for the photosensitivity of CAD. In 11 of 12 patients with CAD, dupilumab was associated with improvement in dermatitis, but only half of patients noted improvement in photosensitivity.
Original languageEnglish
Article numberljae180
Number of pages5
JournalBritish Journal of Dermatology
Early online date24 Apr 2024
Publication statusE-pub ahead of print - 24 Apr 2024


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