Abstract
Vulval cancers are rare, but after primary treatment, known to recur with a high frequency (30%). Clinico-pathological predictors of recurrence have been established to a great extent. However, there is paucity of literature on predictors of early versus late recurrence. We sought to identify such predictors through a retrospective study of vulval cancer recurrences in a single cancer centre over 11 years. Age of women, depth of invasion/site of primary tumour and presence of background VIN/lichen sclerosus do not appear to affect timing of recurrence. However, vulval cancers that recur after 2 years of primary tumour recognition are more likely to be well-differentiated tumours, have undergone radical surgery and have had a closest disease-free margin >1 cm. Late recurrences are entirely local rather than distant metastases and this translates into a better survival as shown in our study (40 months median survival in the early group versus 112 in the late recurrence group).
| Original language | English |
|---|---|
| Pages (from-to) | 518-521 |
| Number of pages | 4 |
| Journal | Journal of Obstetrics & Gynaecology |
| Volume | 36 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2016 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Adult
- Aged
- Aged, 80 and over
- Female
- Humans
- Lichen sclerosus et atrophicus
- Middle aged
- Neoplasm invasiveness
- Neoplasm recurrence, Local
- Retrospective studies
- Risk factors
- Time factors
- Vulvar neoplasms
- Journal article
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