Early sustained recovery following first episode psychosis: Evidence from the AESOP10 follow-up study

J. M. Lappin; M. Heslin; B. Lomas; P. B. Jones; G. A. Doody; U. A. Reininghaus; T. Croudace; T. Craig; P. Fearon; R. M. Murray; P. Dazzan; C. Morgan

doi:10.1016/j.schres.2018.03.014

Early sustained recovery following first episode psychosis: Evidence from the AESOP10 follow-up study

J. M. Lappin (Lead / Corresponding author), M. Heslin, B. Lomas, P. B. Jones, G. A. Doody, U. A. Reininghaus, T. Croudace, T. Craig, P. Fearon, R. M. Murray, P. Dazzan, C. Morgan

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Abstract

Objective: To describe the characteristics of individuals with early sustained recovery following first episode psychosis.

Methods: Individuals with a first episode psychosis were followed-up for ten years. Comparisons were made between those with Early Sustained Recovery and those with Other Course types.

Results: Of 345 individuals, n=43 (12.5%) had Early Sustained Recovery. They were more likely than those with Other Course types to be female (OR=2.45; 95% CI: 1.25-4.81); employed (OR=2.39; 95% CI: 1.22-4.69); in a relationship (OR=2.68; 95% CI: 1.35-5.32); have a short DUP (OR=2.86; 95% CI: 1.37-5.88); and have a diagnosis other than schizophrenia, particularly mania (OR=6.39; 95% CI: 2.52-16.18) or brief psychosis (OR=3.64; 95% CI: 1.10-12.10).

Conclusions: Sustained recovery from first episode psychosis occurs in a minority.

Original language	English
Pages (from-to)	341-345
Number of pages	5
Journal	Schizophrenia Research
Volume	199
Early online date	20 Mar 2018
DOIs	https://doi.org/10.1016/j.schres.2018.03.014
Publication status	Published - Sept 2018

Keywords

Longitudinal follow-up
Medication
Outcomes
Psychosis
Recovery
Schizophrenia

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.schres.2018.03.014

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@article{de74ba22361f4b56b2273610786b18cb,

title = "Early sustained recovery following first episode psychosis: Evidence from the AESOP10 follow-up study",

abstract = "Objective: To describe the characteristics of individuals with early sustained recovery following first episode psychosis.Methods: Individuals with a first episode psychosis were followed-up for ten years. Comparisons were made between those with Early Sustained Recovery and those with Other Course types.Results: Of 345 individuals, n=43 (12.5%) had Early Sustained Recovery. They were more likely than those with Other Course types to be female (OR=2.45; 95% CI: 1.25-4.81); employed (OR=2.39; 95% CI: 1.22-4.69); in a relationship (OR=2.68; 95% CI: 1.35-5.32); have a short DUP (OR=2.86; 95% CI: 1.37-5.88); and have a diagnosis other than schizophrenia, particularly mania (OR=6.39; 95% CI: 2.52-16.18) or brief psychosis (OR=3.64; 95% CI: 1.10-12.10).Conclusions: Sustained recovery from first episode psychosis occurs in a minority.",

keywords = "Longitudinal follow-up, Medication, Outcomes, Psychosis, Recovery, Schizophrenia",

author = "Lappin, {J. M.} and M. Heslin and B. Lomas and Jones, {P. B.} and Doody, {G. A.} and Reininghaus, {U. A.} and T. Croudace and T. Craig and P. Fearon and Murray, {R. M.} and P. Dazzan and C. Morgan",

note = "This work was supported by UK Medical Research Council (Ref: G0500817) and the Department of Health via the National Institute for Health Research (NIHR) Specialist Biomedical Research Centre for Mental Health award to South London and Maudsley NHS Foundation Trust (SLaM) and the Institute of Psychiatry at King's College London. The funding sources did not partake in the design, data collection, or analysis.",

year = "2018",

month = sep,

doi = "10.1016/j.schres.2018.03.014",

language = "English",

volume = "199",

pages = "341--345",

journal = "Schizophrenia Research",

issn = "0920-9964",

publisher = "Elsevier",

}

TY - JOUR

T1 - Early sustained recovery following first episode psychosis

T2 - Evidence from the AESOP10 follow-up study

AU - Lappin, J. M.

AU - Heslin, M.

AU - Lomas, B.

AU - Jones, P. B.

AU - Doody, G. A.

AU - Reininghaus, U. A.

AU - Croudace, T.

AU - Craig, T.

AU - Fearon, P.

AU - Murray, R. M.

AU - Dazzan, P.

AU - Morgan, C.

N1 - This work was supported by UK Medical Research Council (Ref: G0500817) and the Department of Health via the National Institute for Health Research (NIHR) Specialist Biomedical Research Centre for Mental Health award to South London and Maudsley NHS Foundation Trust (SLaM) and the Institute of Psychiatry at King's College London. The funding sources did not partake in the design, data collection, or analysis.

PY - 2018/9

Y1 - 2018/9

N2 - Objective: To describe the characteristics of individuals with early sustained recovery following first episode psychosis.Methods: Individuals with a first episode psychosis were followed-up for ten years. Comparisons were made between those with Early Sustained Recovery and those with Other Course types.Results: Of 345 individuals, n=43 (12.5%) had Early Sustained Recovery. They were more likely than those with Other Course types to be female (OR=2.45; 95% CI: 1.25-4.81); employed (OR=2.39; 95% CI: 1.22-4.69); in a relationship (OR=2.68; 95% CI: 1.35-5.32); have a short DUP (OR=2.86; 95% CI: 1.37-5.88); and have a diagnosis other than schizophrenia, particularly mania (OR=6.39; 95% CI: 2.52-16.18) or brief psychosis (OR=3.64; 95% CI: 1.10-12.10).Conclusions: Sustained recovery from first episode psychosis occurs in a minority.

AB - Objective: To describe the characteristics of individuals with early sustained recovery following first episode psychosis.Methods: Individuals with a first episode psychosis were followed-up for ten years. Comparisons were made between those with Early Sustained Recovery and those with Other Course types.Results: Of 345 individuals, n=43 (12.5%) had Early Sustained Recovery. They were more likely than those with Other Course types to be female (OR=2.45; 95% CI: 1.25-4.81); employed (OR=2.39; 95% CI: 1.22-4.69); in a relationship (OR=2.68; 95% CI: 1.35-5.32); have a short DUP (OR=2.86; 95% CI: 1.37-5.88); and have a diagnosis other than schizophrenia, particularly mania (OR=6.39; 95% CI: 2.52-16.18) or brief psychosis (OR=3.64; 95% CI: 1.10-12.10).Conclusions: Sustained recovery from first episode psychosis occurs in a minority.

KW - Longitudinal follow-up

KW - Medication

KW - Outcomes

KW - Psychosis

KW - Recovery

KW - Schizophrenia

U2 - 10.1016/j.schres.2018.03.014

DO - 10.1016/j.schres.2018.03.014

M3 - Article

C2 - 29571751

SN - 0920-9964

VL - 199

SP - 341

EP - 345

JO - Schizophrenia Research

JF - Schizophrenia Research

ER -

Early sustained recovery following first episode psychosis: Evidence from the AESOP10 follow-up study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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