Editorial Expression of Concern: Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo

Masato Kanemaki; Alberto Sanchez-Diaz; Agnieszka Gambus; Karim Labib

doi:10.1038/s41586-026-10727-w

Editorial Expression of Concern: Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo

Masato Kanemaki
, Alberto Sanchez-Diaz
, Agnieszka Gambus
, Karim Labib (Lead / Corresponding author)

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

The Editors are issuing this expression of concern. After publication of this article, concerns were raised regarding duplications of images representing different samples, specifically in Fig. 1a and Supplementary Fig. S1. The authors were able to provide supporting data for some samples, which resolved most of the concerns raised. However, due to a lack of raw data for all samples, the following concern remains. Supplementary Fig. 1, duplication of UBR1-OFF-37°C, yjr072c-td, and UBR1-OFF-37°C yml023C-td. The readers are therefore advised to interpret the data for yjr072c-td and yml023C-td with caution. All the authors agree with this Editorial Expression of Concern.

Original language	English
Pages (from-to)	E21
Journal	Nature
Volume	654
Issue number	8119
Early online date	3 Jun 2026
DOIs	https://doi.org/10.1038/s41586-026-10727-w
Publication status	Published - 18 Jun 2026

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title = "Editorial Expression of Concern: Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo",

abstract = "The Editors are issuing this expression of concern. After publication of this article, concerns were raised regarding duplications of images representing different samples, specifically in Fig. 1a and Supplementary Fig. S1. The authors were able to provide supporting data for some samples, which resolved most of the concerns raised. However, due to a lack of raw data for all samples, the following concern remains. Supplementary Fig. 1, duplication of UBR1-OFF-37°C, yjr072c-td, and UBR1-OFF-37°C yml023C-td. The readers are therefore advised to interpret the data for yjr072c-td and yml023C-td with caution. All the authors agree with this Editorial Expression of Concern.",

author = "Masato Kanemaki and Alberto Sanchez-Diaz and Agnieszka Gambus and Karim Labib",

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TY - JOUR

T1 - Editorial Expression of Concern

T2 - Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo

AU - Kanemaki, Masato

AU - Sanchez-Diaz, Alberto

AU - Gambus, Agnieszka

AU - Labib, Karim

PY - 2026/6/18

Y1 - 2026/6/18

N2 - The Editors are issuing this expression of concern. After publication of this article, concerns were raised regarding duplications of images representing different samples, specifically in Fig. 1a and Supplementary Fig. S1. The authors were able to provide supporting data for some samples, which resolved most of the concerns raised. However, due to a lack of raw data for all samples, the following concern remains. Supplementary Fig. 1, duplication of UBR1-OFF-37°C, yjr072c-td, and UBR1-OFF-37°C yml023C-td. The readers are therefore advised to interpret the data for yjr072c-td and yml023C-td with caution. All the authors agree with this Editorial Expression of Concern.

AB - The Editors are issuing this expression of concern. After publication of this article, concerns were raised regarding duplications of images representing different samples, specifically in Fig. 1a and Supplementary Fig. S1. The authors were able to provide supporting data for some samples, which resolved most of the concerns raised. However, due to a lack of raw data for all samples, the following concern remains. Supplementary Fig. 1, duplication of UBR1-OFF-37°C, yjr072c-td, and UBR1-OFF-37°C yml023C-td. The readers are therefore advised to interpret the data for yjr072c-td and yml023C-td with caution. All the authors agree with this Editorial Expression of Concern.

UR - https://www.scopus.com/pages/publications/105041129764

U2 - 10.1038/s41586-026-10727-w

DO - 10.1038/s41586-026-10727-w

M3 - Comment/debate

C2 - 42236950

SN - 0028-0836

VL - 654

SP - E21

JO - Nature

JF - Nature

IS - 8119

ER -

Editorial Expression of Concern: Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo

Abstract

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