Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction

J. S. Chatterjee, A. Lee, W. Anderson, L. Baker, J. H. Stevenson, J. A. Dewar, A. M. Thompson

    Research output: Contribution to journalArticle

    51 Citations (Scopus)

    Abstract

    Background: The effect of postoperative radiotherapy following autologous flap breast reconstruction is controversial. The aim of this study, was to measure whether adjuvant radiotherapy following immediate deep inferior epigastric perforator (DIEP) free flap breast reconstruction affected flap Volume.

    Methods: Sixty-eight women underwent immediate autologous DIEP flap reconstruction following mastectomy for breast cancer. Twenty-two of the 68 received postoperative radiotherapy (45Gy in 20 fractions over 4 weeks). Intraoperative flap volume data were collected prospectively. Volumetric assessment was carried out a minimum of I year after surgery. Patients who had volume adjustment: surgery, after initial reconstruction were analysed separately.

    Results: The mean age of the women was 52 (range 37-69) years and median follow-up was 3.5 (range 1 - 10) years. There was no statistically significant difference in Volume change between patients who had and those who did not have postreconstruction radiotherapy for the whole cohort (median reduction 65 versus 0 ml) or when women who had undergone further Volume adjustment surgery were excluded.

    Conclusion: In this study postoperative radiotherapy did not significantly affect breast Volume after DIEP flap reconstruction. The potential need for postoperative radiotherapy should not deter from undergoing immediate DIEP flap breast reconstruction.

    Original languageEnglish
    Pages (from-to)1135-1140
    Number of pages6
    JournalBritish Journal of Surgery
    Volume96
    Issue number10
    DOIs
    Publication statusPublished - Oct 2009

    Keywords

    • ADJUVANT RADIOTHERAPY
    • RADIATION-THERAPY
    • MASTECTOMY
    • CANCER

    Cite this

    Chatterjee, J. S., Lee, A., Anderson, W., Baker, L., Stevenson, J. H., Dewar, J. A., & Thompson, A. M. (2009). Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction. British Journal of Surgery, 96(10), 1135-1140. https://doi.org/10.1002/bjs.6693
    Chatterjee, J. S. ; Lee, A. ; Anderson, W. ; Baker, L. ; Stevenson, J. H. ; Dewar, J. A. ; Thompson, A. M. . / Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction. In: British Journal of Surgery. 2009 ; Vol. 96, No. 10. pp. 1135-1140.
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    title = "Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction",
    abstract = "Background: The effect of postoperative radiotherapy following autologous flap breast reconstruction is controversial. The aim of this study, was to measure whether adjuvant radiotherapy following immediate deep inferior epigastric perforator (DIEP) free flap breast reconstruction affected flap Volume.Methods: Sixty-eight women underwent immediate autologous DIEP flap reconstruction following mastectomy for breast cancer. Twenty-two of the 68 received postoperative radiotherapy (45Gy in 20 fractions over 4 weeks). Intraoperative flap volume data were collected prospectively. Volumetric assessment was carried out a minimum of I year after surgery. Patients who had volume adjustment: surgery, after initial reconstruction were analysed separately.Results: The mean age of the women was 52 (range 37-69) years and median follow-up was 3.5 (range 1 - 10) years. There was no statistically significant difference in Volume change between patients who had and those who did not have postreconstruction radiotherapy for the whole cohort (median reduction 65 versus 0 ml) or when women who had undergone further Volume adjustment surgery were excluded.Conclusion: In this study postoperative radiotherapy did not significantly affect breast Volume after DIEP flap reconstruction. The potential need for postoperative radiotherapy should not deter from undergoing immediate DIEP flap breast reconstruction.",
    keywords = "ADJUVANT RADIOTHERAPY, RADIATION-THERAPY, MASTECTOMY, CANCER",
    author = "Chatterjee, {J. S.} and A. Lee and W. Anderson and L. Baker and Stevenson, {J. H.} and Dewar, {J. A.} and Thompson, {A. M.}",
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    Chatterjee, JS, Lee, A, Anderson, W, Baker, L, Stevenson, JH, Dewar, JA & Thompson, AM 2009, 'Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction', British Journal of Surgery, vol. 96, no. 10, pp. 1135-1140. https://doi.org/10.1002/bjs.6693

    Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction. / Chatterjee, J. S.; Lee, A.; Anderson, W.; Baker, L.; Stevenson, J. H.; Dewar, J. A. ; Thompson, A. M. .

    In: British Journal of Surgery, Vol. 96, No. 10, 10.2009, p. 1135-1140.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction

    AU - Chatterjee, J. S.

    AU - Lee, A.

    AU - Anderson, W.

    AU - Baker, L.

    AU - Stevenson, J. H.

    AU - Dewar, J. A.

    AU - Thompson, A. M.

    PY - 2009/10

    Y1 - 2009/10

    N2 - Background: The effect of postoperative radiotherapy following autologous flap breast reconstruction is controversial. The aim of this study, was to measure whether adjuvant radiotherapy following immediate deep inferior epigastric perforator (DIEP) free flap breast reconstruction affected flap Volume.Methods: Sixty-eight women underwent immediate autologous DIEP flap reconstruction following mastectomy for breast cancer. Twenty-two of the 68 received postoperative radiotherapy (45Gy in 20 fractions over 4 weeks). Intraoperative flap volume data were collected prospectively. Volumetric assessment was carried out a minimum of I year after surgery. Patients who had volume adjustment: surgery, after initial reconstruction were analysed separately.Results: The mean age of the women was 52 (range 37-69) years and median follow-up was 3.5 (range 1 - 10) years. There was no statistically significant difference in Volume change between patients who had and those who did not have postreconstruction radiotherapy for the whole cohort (median reduction 65 versus 0 ml) or when women who had undergone further Volume adjustment surgery were excluded.Conclusion: In this study postoperative radiotherapy did not significantly affect breast Volume after DIEP flap reconstruction. The potential need for postoperative radiotherapy should not deter from undergoing immediate DIEP flap breast reconstruction.

    AB - Background: The effect of postoperative radiotherapy following autologous flap breast reconstruction is controversial. The aim of this study, was to measure whether adjuvant radiotherapy following immediate deep inferior epigastric perforator (DIEP) free flap breast reconstruction affected flap Volume.Methods: Sixty-eight women underwent immediate autologous DIEP flap reconstruction following mastectomy for breast cancer. Twenty-two of the 68 received postoperative radiotherapy (45Gy in 20 fractions over 4 weeks). Intraoperative flap volume data were collected prospectively. Volumetric assessment was carried out a minimum of I year after surgery. Patients who had volume adjustment: surgery, after initial reconstruction were analysed separately.Results: The mean age of the women was 52 (range 37-69) years and median follow-up was 3.5 (range 1 - 10) years. There was no statistically significant difference in Volume change between patients who had and those who did not have postreconstruction radiotherapy for the whole cohort (median reduction 65 versus 0 ml) or when women who had undergone further Volume adjustment surgery were excluded.Conclusion: In this study postoperative radiotherapy did not significantly affect breast Volume after DIEP flap reconstruction. The potential need for postoperative radiotherapy should not deter from undergoing immediate DIEP flap breast reconstruction.

    KW - ADJUVANT RADIOTHERAPY

    KW - RADIATION-THERAPY

    KW - MASTECTOMY

    KW - CANCER

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    DO - 10.1002/bjs.6693

    M3 - Article

    VL - 96

    SP - 1135

    EP - 1140

    JO - British Journal of Surgery

    JF - British Journal of Surgery

    SN - 0007-1323

    IS - 10

    ER -