TY - JOUR
T1 - Effect of radiotherapy on oral mucosa assessed by quantitative exfoliative cytology
AU - Ogden, G.R.
AU - Cowpe, J.G.
AU - Green, Michael
PY - 1989/1/1
Y1 - 1989/1/1
N2 - The effect of radiotherapy on normal buccal mucosa was investigated using the quantitative techniques of cytomorphology (measurement of nuclear and cytoplasmic area) and DNA cytophotometry. These techniques were applied to smears obtained before, during, and after irradiation. Nuclear area and cytoplasmic area increased and DNA values were abnormal in most cases as a result of radiotherapy, returning to within normal limits one month after treatment. This contrasts strongly with the changes seen in smears from previously irradiated uterine cervices, where changes in cytomorphology may persist for several years.
AB - The effect of radiotherapy on normal buccal mucosa was investigated using the quantitative techniques of cytomorphology (measurement of nuclear and cytoplasmic area) and DNA cytophotometry. These techniques were applied to smears obtained before, during, and after irradiation. Nuclear area and cytoplasmic area increased and DNA values were abnormal in most cases as a result of radiotherapy, returning to within normal limits one month after treatment. This contrasts strongly with the changes seen in smears from previously irradiated uterine cervices, where changes in cytomorphology may persist for several years.
UR - http://www.scopus.com/inward/record.url?scp=0024412985&partnerID=8YFLogxK
U2 - 10.1136/jcp.42.9.940
DO - 10.1136/jcp.42.9.940
M3 - Article
AN - SCOPUS:0024412985
SN - 0021-9746
VL - 42
SP - 940
EP - 943
JO - Journal of Clinical Pathology
JF - Journal of Clinical Pathology
IS - 9
ER -