Effect of the hybrid composition on the physicochemical properties and morphology of iron oxide-gold nanoparticles

C.M. Barnett, M. Gueorguieva, M. R. Lees, D.J. McGarvey, C. Hoskins

    Research output: Contribution to journalArticle

    9 Citations (Scopus)

    Abstract

    Hybrid nanoparticles (HNPs) formed from iron oxide cores and gold nano-shells are becoming increasingly applicable in biomedicine. However, little investigation has been carried out on the effects of the constituent components on their physical characteristics. Here we determine the effect of polymer intermediate, gold nano-shell thickness and magnetic iron oxide core diameter on the morphological and physical properties of these nano-hybrids. Our findings suggest that the use of polymer intermediate directly impacts the morphology of the nanostructure formed. Here, we observed the formation of nanosphere and nano-star structures by varying the cationic polymer intermediate. The nano-stars formed have a larger magnetic coercivity, T relaxivity and exhibited a unique characteristic nano-heating pattern upon laser irradiation. Increasing the iron oxide core diameter resulted in a greater T relaxivity enhanced and nanoheating capabilities due to increased surface area. Increasing the gold nano-shell thickness resulted in a decreased efficiency as a nano-heater along with a decrease in T relaxivity. These results highlight the importance of identifying the key traits required when fabricating HNPs in order to tailor them to specific applications.
    Original languageEnglish
    JournalJournal of Nanoparticle Research
    Volume14
    Issue number10
    DOIs
    Publication statusPublished - 2012

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    Gold Nanoparticles
    Iron oxides
    iron oxides
    Gold
    Iron
    Oxides
    Shell
    Polymers
    gold
    Nanoparticles
    nanoparticles
    Stars
    Star
    polymers
    Chemical analysis
    stars
    Coercivity
    Nanospheres
    Laser beam effects
    Surface area

    Cite this

    Barnett, C.M. ; Gueorguieva, M. ; Lees, M. R. ; McGarvey, D.J. ; Hoskins, C. / Effect of the hybrid composition on the physicochemical properties and morphology of iron oxide-gold nanoparticles. In: Journal of Nanoparticle Research. 2012 ; Vol. 14, No. 10.
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    abstract = "Hybrid nanoparticles (HNPs) formed from iron oxide cores and gold nano-shells are becoming increasingly applicable in biomedicine. However, little investigation has been carried out on the effects of the constituent components on their physical characteristics. Here we determine the effect of polymer intermediate, gold nano-shell thickness and magnetic iron oxide core diameter on the morphological and physical properties of these nano-hybrids. Our findings suggest that the use of polymer intermediate directly impacts the morphology of the nanostructure formed. Here, we observed the formation of nanosphere and nano-star structures by varying the cationic polymer intermediate. The nano-stars formed have a larger magnetic coercivity, T relaxivity and exhibited a unique characteristic nano-heating pattern upon laser irradiation. Increasing the iron oxide core diameter resulted in a greater T relaxivity enhanced and nanoheating capabilities due to increased surface area. Increasing the gold nano-shell thickness resulted in a decreased efficiency as a nano-heater along with a decrease in T relaxivity. These results highlight the importance of identifying the key traits required when fabricating HNPs in order to tailor them to specific applications.",
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    Effect of the hybrid composition on the physicochemical properties and morphology of iron oxide-gold nanoparticles. / Barnett, C.M.; Gueorguieva, M.; Lees, M. R.; McGarvey, D.J.; Hoskins, C.

    In: Journal of Nanoparticle Research, Vol. 14, No. 10, 2012.

    Research output: Contribution to journalArticle

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    T1 - Effect of the hybrid composition on the physicochemical properties and morphology of iron oxide-gold nanoparticles

    AU - Barnett, C.M.

    AU - Gueorguieva, M.

    AU - Lees, M. R.

    AU - McGarvey, D.J.

    AU - Hoskins, C.

    N1 - Copyright 2012 Elsevier B.V., All rights reserved.

    PY - 2012

    Y1 - 2012

    N2 - Hybrid nanoparticles (HNPs) formed from iron oxide cores and gold nano-shells are becoming increasingly applicable in biomedicine. However, little investigation has been carried out on the effects of the constituent components on their physical characteristics. Here we determine the effect of polymer intermediate, gold nano-shell thickness and magnetic iron oxide core diameter on the morphological and physical properties of these nano-hybrids. Our findings suggest that the use of polymer intermediate directly impacts the morphology of the nanostructure formed. Here, we observed the formation of nanosphere and nano-star structures by varying the cationic polymer intermediate. The nano-stars formed have a larger magnetic coercivity, T relaxivity and exhibited a unique characteristic nano-heating pattern upon laser irradiation. Increasing the iron oxide core diameter resulted in a greater T relaxivity enhanced and nanoheating capabilities due to increased surface area. Increasing the gold nano-shell thickness resulted in a decreased efficiency as a nano-heater along with a decrease in T relaxivity. These results highlight the importance of identifying the key traits required when fabricating HNPs in order to tailor them to specific applications.

    AB - Hybrid nanoparticles (HNPs) formed from iron oxide cores and gold nano-shells are becoming increasingly applicable in biomedicine. However, little investigation has been carried out on the effects of the constituent components on their physical characteristics. Here we determine the effect of polymer intermediate, gold nano-shell thickness and magnetic iron oxide core diameter on the morphological and physical properties of these nano-hybrids. Our findings suggest that the use of polymer intermediate directly impacts the morphology of the nanostructure formed. Here, we observed the formation of nanosphere and nano-star structures by varying the cationic polymer intermediate. The nano-stars formed have a larger magnetic coercivity, T relaxivity and exhibited a unique characteristic nano-heating pattern upon laser irradiation. Increasing the iron oxide core diameter resulted in a greater T relaxivity enhanced and nanoheating capabilities due to increased surface area. Increasing the gold nano-shell thickness resulted in a decreased efficiency as a nano-heater along with a decrease in T relaxivity. These results highlight the importance of identifying the key traits required when fabricating HNPs in order to tailor them to specific applications.

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