Abstract
There is considerable evidence that statins can reduce cardiovascular events. Currently high-risk patients are treated to a target cholesterol concentration. An alternative prescribing strategy (the 'fire-and-forget' approach) would instead deploy low-dose statins more widely. It has been suggested that for the same cost this approach might prevent more cardiovascular events. We have compared the treat-to-target and fire-and-forget statin prescribing strategies with respect to adherence and cardiovascular outcomes.
Original language | English |
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Pages (from-to) | 385-392 |
Number of pages | 8 |
Journal | Pharmacoepidemiology and Drug Safety |
Volume | 16 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2007 |
Keywords
- Cardiovascular Diseases
- Cholesterol
- Cohort Studies
- Databases as Topic
- Drug Administration Schedule
- Drug Prescriptions
- Drug Utilization
- Female
- Follow-Up Studies
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Hypercholesterolemia
- Male
- Medical Records Systems, Computerized
- Middle Aged
- Odds Ratio
- Patient Compliance
- Physician's Practice Patterns
- Proportional Hazards Models
- Risk Assessment
- Scotland
- Time Factors
- Treatment Outcome