Effectiveness of two statin prescribing strategies with respect to adherence and cardiovascular outcomes: observational study

L Wei, T. M. MacDonald, A. D. Watson, M J Murphy

    Research output: Contribution to journalArticle

    26 Citations (Scopus)

    Abstract

    There is considerable evidence that statins can reduce cardiovascular events. Currently high-risk patients are treated to a target cholesterol concentration. An alternative prescribing strategy (the 'fire-and-forget' approach) would instead deploy low-dose statins more widely. It has been suggested that for the same cost this approach might prevent more cardiovascular events. We have compared the treat-to-target and fire-and-forget statin prescribing strategies with respect to adherence and cardiovascular outcomes.
    Original languageEnglish
    Pages (from-to)385-392
    Number of pages8
    JournalPharmacoepidemiology and Drug Safety
    Volume16
    Issue number4
    DOIs
    Publication statusPublished - 2007

    Keywords

    • Cardiovascular Diseases
    • Cholesterol
    • Cohort Studies
    • Databases as Topic
    • Drug Administration Schedule
    • Drug Prescriptions
    • Drug Utilization
    • Female
    • Follow-Up Studies
    • Humans
    • Hydroxymethylglutaryl-CoA Reductase Inhibitors
    • Hypercholesterolemia
    • Male
    • Medical Records Systems, Computerized
    • Middle Aged
    • Odds Ratio
    • Patient Compliance
    • Physician's Practice Patterns
    • Proportional Hazards Models
    • Risk Assessment
    • Scotland
    • Time Factors
    • Treatment Outcome

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