Effects of acute hypoglycaemia on auditory information processing in adults with Type I diabetes

M. W. Strachan, F. M. Ewing, B. M. Frier, R. J. McCrimmon, I. J. Deary (Lead / Corresponding author)

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    29 Citations (Scopus)

    Abstract

    AIMS/HYPOTHESIS: Acute hypoglycaemia in humans causes general impairment of cognitive function, but information about its effects on more specific cognitive processes is limited. METHODS: Basic aspects of auditory function were studied in 15 adults with uncomplicated Type I (insulin-dependent) diabetes mellitus. Two separate hyperinsulinaemic glucose clamp procedures were done on different study days, in a counterbalanced fashion, either maintaining euglycaemia (blood glucose 5.0 mmol x l(-1)) or inducing hypoglycaemia (blood glucose 2.6 mmol x l(-1)). During each study, the subjects performed a battery of auditory and cognitive function tasks. RESULTS: Hypoglycaemia caused deterioration in mental efficiency as assessed by Digit Symbol (p
    Original languageEnglish
    Pages (from-to)97-105
    Number of pages9
    JournalDiabetologia
    Volume46
    Issue number1
    DOIs
    Publication statusPublished - Jan 2003

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