TY - JOUR
T1 - Effects of Ar and O2 Plasma Etching on Parylene C
T2 - Topography versus Surface Chemistry and the Impact on Cell Viability
AU - Kontziampasis, Dimitrios
AU - Trantidou, Tatiana
AU - Regoutz, Anna
AU - Humphrey, Eleanor J.
AU - Carta, Daniela
AU - Terracciano, Cesare M.
AU - Prodromakis, Themistoklis
N1 - Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - The effect of O2 and Ar plasma etching on poly(chloro-p-xylylene) (Parylene C) is thoroughly studied by atomic force microscopy, X-ray photoelectron spectroscopy, and static contact angle measurements. Results indicate that O2 plasma changes the topography more drastically than Ar plasma. Furthermore, despite the fact that Ar plasma is expected to be chemically inert, both plasmas introduce O2 to the surface of the Parylene C films, while Ar plasma additionally reduces the amount of Cl present in the polymer. The effect on the viability of cultured cardiomyocytes is also examined, indicating that cells attach and survive both on Ar and O2 treated films in contrast to untreated Parylene. These observations can provide useful insight into the field of material science and tissue engineering. The effects of O2 and Ar plasma on the nanotopography and surface chemistry of Parylene C are studied. Atomic force microscopy and X-ray photoelectron spectroscopy indicate that O2 plasma changes the topography more drastically than Ar plasma. Both plasmas introduce O2 to Parylene, but Ar plasma reduces the amount of Cl. These observations are reflected on the viability of cultured cardiomyocytes.
AB - The effect of O2 and Ar plasma etching on poly(chloro-p-xylylene) (Parylene C) is thoroughly studied by atomic force microscopy, X-ray photoelectron spectroscopy, and static contact angle measurements. Results indicate that O2 plasma changes the topography more drastically than Ar plasma. Furthermore, despite the fact that Ar plasma is expected to be chemically inert, both plasmas introduce O2 to the surface of the Parylene C films, while Ar plasma additionally reduces the amount of Cl present in the polymer. The effect on the viability of cultured cardiomyocytes is also examined, indicating that cells attach and survive both on Ar and O2 treated films in contrast to untreated Parylene. These observations can provide useful insight into the field of material science and tissue engineering. The effects of O2 and Ar plasma on the nanotopography and surface chemistry of Parylene C are studied. Atomic force microscopy and X-ray photoelectron spectroscopy indicate that O2 plasma changes the topography more drastically than Ar plasma. Both plasmas introduce O2 to Parylene, but Ar plasma reduces the amount of Cl. These observations are reflected on the viability of cultured cardiomyocytes.
KW - atomic force microscopy
KW - cell viability
KW - Parylene C
KW - plasma nanoscience
KW - X-ray photoelectron spectroscopy
UR - http://www.scopus.com/inward/record.url?scp=84939539650&partnerID=8YFLogxK
U2 - 10.1002/ppap.201500053
DO - 10.1002/ppap.201500053
M3 - Article
AN - SCOPUS:84939539650
SN - 1612-8850
VL - 13
SP - 324
EP - 333
JO - Plasma Processes and Polymers
JF - Plasma Processes and Polymers
IS - 3
ER -