Effects of blood flow on high intensity focused ultrasound ablation

Shaozhen Song, Jing Gao, Zhihong Huang, Dong-Sheng Jeng, Huijie Zhang

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

    1 Citation (Scopus)

    Abstract

    With the benefits of high accuracy and non-invasive implementation, high intensity focused ultrasound (HIFU) is a promising medical procedure to heat and destroy pathogenic tissue rapidly. However, the relation between the power emitted by the ultrasound transducer and the energy arriving at the target area is complex, interfered by several factors such as the properties of tissue, obstacles of hard tissues or vascularization. In this study, a finite element model was used to simulate the propagation process of focused ultrasound inside tissue phantom and passing the perfused vascular. Then, the resultant sound pressure distribution provided the heat source for heat transfer process simulation. The simulation results were validated with thermocouple measurements in egg white phantoms. This study demonstrated an efficient methodology for estimating the thermal effects in HIFU hyperthermia therapy, especially in the region with large blood vessel. This study will be useful in minimizing difficulties and risks in HIFU induced hyperthermia treatment and facilitate the extension from laboratory to clinic use.
    Original languageEnglish
    Title of host publicationProceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
    Pages2331-2334
    Number of pages4
    Volume4
    DOIs
    Publication statusPublished - 1 Jan 2011

    Fingerprint

    blood flow
    ablation
    hyperthermia
    blood vessels
    eggs
    thermocouples
    sound pressure
    heat sources
    pressure distribution
    temperature effects
    therapy
    transducers
    estimating
    simulation
    heat transfer
    methodology
    heat
    propagation
    energy

    Cite this

    Song, S., Gao, J., Huang, Z., Jeng, D-S., & Zhang, H. (2011). Effects of blood flow on high intensity focused ultrasound ablation. In Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 (Vol. 4, pp. 2331-2334) https://doi.org/10.1109/BMEI.2011.6098766
    Song, Shaozhen ; Gao, Jing ; Huang, Zhihong ; Jeng, Dong-Sheng ; Zhang, Huijie. / Effects of blood flow on high intensity focused ultrasound ablation. Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. Vol. 4 2011. pp. 2331-2334
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    Song, S, Gao, J, Huang, Z, Jeng, D-S & Zhang, H 2011, Effects of blood flow on high intensity focused ultrasound ablation. in Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. vol. 4, pp. 2331-2334. https://doi.org/10.1109/BMEI.2011.6098766

    Effects of blood flow on high intensity focused ultrasound ablation. / Song, Shaozhen; Gao, Jing; Huang, Zhihong; Jeng, Dong-Sheng; Zhang, Huijie.

    Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. Vol. 4 2011. p. 2331-2334.

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

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    Song S, Gao J, Huang Z, Jeng D-S, Zhang H. Effects of blood flow on high intensity focused ultrasound ablation. In Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. Vol. 4. 2011. p. 2331-2334 https://doi.org/10.1109/BMEI.2011.6098766