Elective laparoscopic cholecystectomy: recurrent biliary admissions predispose to difficult cholecystectomy

James Lucocq (Lead / Corresponding author), John Scollay, Pradeep Patil

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    Abstract

    Introduction: Patients undergoing elective laparoscopic cholecystectomy (ELLC) represent a heterogeneous group making it challenging to stratify risk. The aim of this paper is to identify pre-operative factors associated with adverse peri- and post-operative outcomes in patients undergoing ELLC. This knowledge will help stratify risk, guide surgical decision making and better inform the consent process.

    Methods: All patients who underwent ELLC between January 2015 and December 2019 were included in the study. Pre-operative data and both peri- and post-operative outcomes were collected retrospectively from multiple databases using a deterministic records-linkage methodology. Patients were divided into groups based on clinical indication (i.e. biliary colic versus cholecystitis) and adverse outcomes were compared. Multivariate regression models were generated for each adverse outcome using pre-operative independent variables.

    Results: Two-thousand one hundred and sixty-six ELLC were identified. Rates of peri- and post-operative adverse outcomes were significantly higher in the cholecystitis versus biliary colic group and increased with number of admissions of cholecystitis (p < 0.05). Rates of subtotal (29.5%), intra-operative complication (9.8%), post-operative complications (19.6%), prolonged post-operative stay (45.9%) and re-admission (16.4%) were significant in the group of patients with ≥ 2 admissions with cholecystitis.

    Conclusion: Our data demonstrate that patients with repeated biliary admission (particularly cholecystitis) ultimately face an increased risk of a difficult ELLC with associated complications, prolonged post-operative stay and readmissions. These data provide robust evidence that individualised risk assessment and consent are necessary before ELLC. Strategies to minimise recurrent biliary admissions prior to LC should be implemented.

    Original languageEnglish
    Pages (from-to)6403-6409
    Number of pages7
    JournalSurgical Endoscopy
    Volume36
    Early online date13 Jan 2022
    DOIs
    Publication statusPublished - Sept 2022

    Keywords

    • Admissions
    • Cholecystitis
    • Inflammation
    • Laparoscopic cholecystectomy
    • Morbidity
    • Outcomes

    ASJC Scopus subject areas

    • Surgery

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