Thiel-embalmed human cadaveric specimens are used widely for biomedical scientific investigation. This Letter reports electrical impedance measurements of Thiel-embalming solutions from 1 Hz to 32 MHz. Compared with other solutions studied, Thiel solution has the lowest impedance throughout the test spectrum. The electrical conductivity of a Thiel-embalmed liver sample exhibited a relatively flat frequency response from 100 to 500 kHz, which is the frequency range used for electro-surgery and radiofrequency tumour ablation (RFA). It measured 5 Sm-1 compared with 0.22 Sm-1 obtained from ex-vivo fresh pig liver. Using finite element modelling and experimental evaluation, the ablation zone obtained from the Thiel-embalmed liver sample was extremely small due to its much higher conductivity. Hence, it is concluded that Thiel-embalmed tissue cannot be used as a reliable model for RFA evaluation.
- Electrical conductivity
- RADIOFREQUENCY ABLATION
- physiological model
- thiel method
Wang, Z., Luo, H., Nick, M., Gueorguieva, M., Andre, P., Baker, R. T., McLean, D., Brown, S., & Cuschieri, A. (2014). Electrical conductivity measurement in Thiel-embalmed tissue model: relevance to radiofrequency ablation. Electronics Letters, 50(16), 1125-1127. https://doi.org/10.1049/el.2014.1934