Endovascular therapy for acute stroke

Maria Politi, Andreas Kastrup, Konstantinos Marmagkiolis, Iris Q Grunwald, Panagiotis Papanagiotou (Lead / Corresponding author)

Research output: Contribution to journalReview articlepeer-review

9 Citations (Scopus)


Stroke is the most common cause of permanent disability, the second most common cause of dementia, and the fourth most common cause of death in the Western world. Recently, based on positive multicenter randomized clinical trials, endovascular therapy for acute stroke has undergone a revolution. Routine mechanical thrombectomy in addition to intravenous thrombolysis has been shown to provide excellent outcomes for patients with proximal anterior circulation occlusions. This procedure reduces disability and benefits are seen across a wide range of age and initial stroke severity. Important features that affect treatment decisions include time of presentation, the patient's clinical status, imaging characteristics, and lab tests. Under optimal conditions, it should be available to patients 24/7, similar to systems offering prompt percutaneous coronary interventions to patients with acute ST-segment elevation myocardial infarctions.

Original languageEnglish
Pages (from-to)534-541
Number of pages8
JournalProgress in cardiovascular diseases
Issue number6
Early online date30 Mar 2017
Publication statusPublished - 22 Jun 2017


  • Cost-Benefit Analysis
  • Disability Evaluation
  • Endovascular Procedures/adverse effects
  • Health Care Costs
  • Humans
  • Recovery of Function
  • Stroke/diagnosis
  • Time Factors
  • Treatment Outcome


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