Engineered muscle: a tool for studying muscle physiology and function

Alastair Khodabukus, Jennifer Z. Paxton, Kenneth Donnelly, Keith Baar

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)

    Abstract

    Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to further our understanding of the molecular mechanisms underlying skeletal muscle adaptation in response to exercise.
    Original languageEnglish
    Pages (from-to)186-191
    Number of pages6
    JournalExercise and Sport Sciences Reviews
    Volume35
    Issue number4
    DOIs
    Publication statusPublished - Oct 2007

    Keywords

    • Exercise
    • Muscle physiology
    • Tissue engineering
    • Fibre type
    • Muscle development
    • Muscle function

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