Epidemiology and Microbiology of Bacterial Bloodstream Infection in a Tertiary Hospital in Nigeria

Garba Iliyasu, Farouq Muhammad Dayyab, Aliyu Aminu, Sadiq Halilu, Salisu Abubakar, Salisu Inuwa, Abdulrazaq Garba Habib

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background
    Bacterial bloodstream infections (BSIs) are a significant cause of morbidity and mortality among hospitalized patients, and data in resource-limited countries are sparse.

    Methods
    A hospital-wide retrospective analysis of microbiologically proven bacteremia was conducted. Sociodemographic data, comorbidities, bacterial isolates, and their antimicrobial susceptibility pattern were recorded.

    Results
    Of the 276 episodes of bacteremia studied, 130 (47.1%) occurred in females. The overall mean age was 15.29 ± 23.22 years. Community-acquired BSI was seen in 179 (65.0%) of the patients, whereas 97 (35%) was hospital-acquired BSI. Gram-negative bacteria 158 (57.2%) were the leading cause of BSI. More than 60% of the isolates were resistant to commonly prescribed antibiotics, especially trimethoprim-sulfamethoxazole, ampicillin, and amoxicillin–clavulanic acid.

    Conclusions
    Gram-negative bacteria are the leading cause of bacteremia with resistance to commonly prescribed antibiotics.
    Original languageEnglish
    Pages (from-to)16-21
    Number of pages6
    JournalInfectious Diseases in Clinical Practice
    Volume28
    Issue number1
    DOIs
    Publication statusPublished - Jan 2020

    Keywords

    • antimicrobial resistance
    • bloodstream infections
    • community-acquired bloodstream infections
    • hospital-acquired bloodstream infections
    • multidrug resistance

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