Epidemiology and Microbiology of Bacterial Bloodstream Infection in a Tertiary Hospital in Nigeria

Garba Iliyasu; Farouq Muhammad Dayyab; Aliyu Aminu; Sadiq Halilu; Salisu Abubakar; Salisu Inuwa; Abdulrazaq Garba Habib

doi:10.1097/IPC.0000000000000783

Epidemiology and Microbiology of Bacterial Bloodstream Infection in a Tertiary Hospital in Nigeria

Garba Iliyasu, Farouq Muhammad Dayyab, Aliyu Aminu, Sadiq Halilu, Salisu Abubakar, Salisu Inuwa, Abdulrazaq Garba Habib

Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Bacterial bloodstream infections (BSIs) are a significant cause of morbidity and mortality among hospitalized patients, and data in resource-limited countries are sparse.

Methods: A hospital-wide retrospective analysis of microbiologically proven bacteremia was conducted. Sociodemographic data, comorbidities, bacterial isolates, and their antimicrobial susceptibility pattern were recorded.

Results: Of the 276 episodes of bacteremia studied, 130 (47.1%) occurred in females. The overall mean age was 15.29 ± 23.22 years. Community-acquired BSI was seen in 179 (65.0%) of the patients, whereas 97 (35%) was hospital-acquired BSI. Gram-negative bacteria 158 (57.2%) were the leading cause of BSI. More than 60% of the isolates were resistant to commonly prescribed antibiotics, especially trimethoprim-sulfamethoxazole, ampicillin, and amoxicillin–clavulanic acid.

Conclusions: Gram-negative bacteria are the leading cause of bacteremia with resistance to commonly prescribed antibiotics.

Original language	English
Pages (from-to)	16-21
Number of pages	6
Journal	Infectious Diseases in Clinical Practice
Volume	28
Issue number	1
DOIs	https://doi.org/10.1097/IPC.0000000000000783
Publication status	Published - Jan 2020

Keywords

antimicrobial resistance
bloodstream infections
community-acquired bloodstream infections
hospital-acquired bloodstream infections
multidrug resistance

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/IPC.0000000000000783

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title = "Epidemiology and Microbiology of Bacterial Bloodstream Infection in a Tertiary Hospital in Nigeria",

abstract = "Background: Bacterial bloodstream infections (BSIs) are a significant cause of morbidity and mortality among hospitalized patients, and data in resource-limited countries are sparse.Methods: A hospital-wide retrospective analysis of microbiologically proven bacteremia was conducted. Sociodemographic data, comorbidities, bacterial isolates, and their antimicrobial susceptibility pattern were recorded.Results: Of the 276 episodes of bacteremia studied, 130 (47.1%) occurred in females. The overall mean age was 15.29 ± 23.22 years. Community-acquired BSI was seen in 179 (65.0%) of the patients, whereas 97 (35%) was hospital-acquired BSI. Gram-negative bacteria 158 (57.2%) were the leading cause of BSI. More than 60% of the isolates were resistant to commonly prescribed antibiotics, especially trimethoprim-sulfamethoxazole, ampicillin, and amoxicillin–clavulanic acid.Conclusions: Gram-negative bacteria are the leading cause of bacteremia with resistance to commonly prescribed antibiotics.",

keywords = "antimicrobial resistance, bloodstream infections, community-acquired bloodstream infections, hospital-acquired bloodstream infections, multidrug resistance",

author = "Garba Iliyasu and Dayyab, {Farouq Muhammad} and Aliyu Aminu and Sadiq Halilu and Salisu Abubakar and Salisu Inuwa and Habib, {Abdulrazaq Garba}",

year = "2020",

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doi = "10.1097/IPC.0000000000000783",

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volume = "28",

pages = "16--21",

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T1 - Epidemiology and Microbiology of Bacterial Bloodstream Infection in a Tertiary Hospital in Nigeria

AU - Iliyasu, Garba

AU - Dayyab, Farouq Muhammad

AU - Aminu, Aliyu

AU - Halilu, Sadiq

AU - Abubakar, Salisu

AU - Inuwa, Salisu

AU - Habib, Abdulrazaq Garba

PY - 2020/1

Y1 - 2020/1

N2 - Background: Bacterial bloodstream infections (BSIs) are a significant cause of morbidity and mortality among hospitalized patients, and data in resource-limited countries are sparse.Methods: A hospital-wide retrospective analysis of microbiologically proven bacteremia was conducted. Sociodemographic data, comorbidities, bacterial isolates, and their antimicrobial susceptibility pattern were recorded.Results: Of the 276 episodes of bacteremia studied, 130 (47.1%) occurred in females. The overall mean age was 15.29 ± 23.22 years. Community-acquired BSI was seen in 179 (65.0%) of the patients, whereas 97 (35%) was hospital-acquired BSI. Gram-negative bacteria 158 (57.2%) were the leading cause of BSI. More than 60% of the isolates were resistant to commonly prescribed antibiotics, especially trimethoprim-sulfamethoxazole, ampicillin, and amoxicillin–clavulanic acid.Conclusions: Gram-negative bacteria are the leading cause of bacteremia with resistance to commonly prescribed antibiotics.

AB - Background: Bacterial bloodstream infections (BSIs) are a significant cause of morbidity and mortality among hospitalized patients, and data in resource-limited countries are sparse.Methods: A hospital-wide retrospective analysis of microbiologically proven bacteremia was conducted. Sociodemographic data, comorbidities, bacterial isolates, and their antimicrobial susceptibility pattern were recorded.Results: Of the 276 episodes of bacteremia studied, 130 (47.1%) occurred in females. The overall mean age was 15.29 ± 23.22 years. Community-acquired BSI was seen in 179 (65.0%) of the patients, whereas 97 (35%) was hospital-acquired BSI. Gram-negative bacteria 158 (57.2%) were the leading cause of BSI. More than 60% of the isolates were resistant to commonly prescribed antibiotics, especially trimethoprim-sulfamethoxazole, ampicillin, and amoxicillin–clavulanic acid.Conclusions: Gram-negative bacteria are the leading cause of bacteremia with resistance to commonly prescribed antibiotics.

KW - antimicrobial resistance

KW - bloodstream infections

KW - community-acquired bloodstream infections

KW - hospital-acquired bloodstream infections

KW - multidrug resistance

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Epidemiology and Microbiology of Bacterial Bloodstream Infection in a Tertiary Hospital in Nigeria

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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