Epidemiology of basal and cutaneous squamous cell carcinoma in the U.K. 2013–15: a cohort study

Z. C. Venables (Lead / Corresponding author), T. Nijsten, K. F. Wong, P. Autier, J. Broggio, A. Deas, C. Harwood, L. M. Hollestein, S. M. Langan, E. Morgan, C. Proby, J. Rashbass, I. M. Leigh

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29 Citations (Scopus)
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Abstract

Background: Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), together known as keratinocyte cancers (KCs), are the commonest cancer in white ethnic populations. Recent improvements to registry data collection in England has allowed more accurate analysis of the epidemiology of BCC and cSCC and for the first time we are able to provide an accurate (representative) tumour burden for KC in the U.K.

Objectives: To estimate the incidence of BCC and cSCC in the U.K.

Methods: A cohort of patients with KCs between 2013 and 2015 were identified using linkage to diagnostic codes derived from pathology reports collected into the national cancer registry. Data from England's cancer registry were combined with data from Scotland, Northern Ireland and Wales. European age-standardized incidence rates (EASRs) of the first BCC and cSCC per patient per annum (PPPA) were calculated.

Results: In the U.K, the EASR of the first BCC and cSCC PPPA in 2013–15 were 285 and 77 per 100 000 person years, respectively (211 120 KCs total in 2015). The mean annual percentage increase was 5% between 2013 and 2015 for both BCC and cSCC. By counting the first KC PPPA, we include an additional 51% KCs compared with the previous reporting technique which counts only the first BCC and cSCC in a patient's lifetime, yet it represents a probable underestimation of 5–11% of the true tumour count.

Conclusions: Based on an improved methodology, a more representative incidence of KC is presented, which is essential to healthcare planning and will lead to improved understanding of the epidemiology of KC.

Original languageEnglish
Pages (from-to)474-482
Number of pages9
JournalBritish Journal of Dermatology
Volume181
Issue number3
Early online date12 Mar 2019
DOIs
Publication statusPublished - 1 Sep 2019

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