Epoprostenol (prostacyclin) and severe arterial disease: a double-blind trial

J. J. F. Belch, B. McArdle, J. G. Pollock, C. D. Forbes, A. Mckay, P. Leiberman, G. D. O. Lowe, C. R. M. Prentice

    Research output: Contribution to journalArticle

    103 Citations (Scopus)

    Abstract

    A 96 h infusion of epoprostenol (prostacyclin) or placebo was given as a treatment for rest pain to 28 patients with severe peripheral arterial disease. 24 h after the end of the infusion patients given epoprostenol had significantly less pain and took fewer analgesics tablets than did the controls. In some patients the epoprostenol effect lasted for over 1 month.
    Original languageEnglish
    Pages (from-to)315-317
    Number of pages3
    JournalLancet
    Volume321
    Issue number8320
    DOIs
    Publication statusPublished - 1983

    Cite this

    Belch, J. J. F., McArdle, B., Pollock, J. G., Forbes, C. D., Mckay, A., Leiberman, P., ... Prentice, C. R. M. (1983). Epoprostenol (prostacyclin) and severe arterial disease: a double-blind trial. Lancet, 321(8320), 315-317. https://doi.org/10.1016/S0140-6736(83)91625-2
    Belch, J. J. F. ; McArdle, B. ; Pollock, J. G. ; Forbes, C. D. ; Mckay, A. ; Leiberman, P. ; Lowe, G. D. O. ; Prentice, C. R. M. / Epoprostenol (prostacyclin) and severe arterial disease : a double-blind trial. In: Lancet. 1983 ; Vol. 321, No. 8320. pp. 315-317.
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    title = "Epoprostenol (prostacyclin) and severe arterial disease: a double-blind trial",
    abstract = "A 96 h infusion of epoprostenol (prostacyclin) or placebo was given as a treatment for rest pain to 28 patients with severe peripheral arterial disease. 24 h after the end of the infusion patients given epoprostenol had significantly less pain and took fewer analgesics tablets than did the controls. In some patients the epoprostenol effect lasted for over 1 month.",
    author = "Belch, {J. J. F.} and B. McArdle and Pollock, {J. G.} and Forbes, {C. D.} and A. Mckay and P. Leiberman and Lowe, {G. D. O.} and Prentice, {C. R. M.}",
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    language = "English",
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    Belch, JJF, McArdle, B, Pollock, JG, Forbes, CD, Mckay, A, Leiberman, P, Lowe, GDO & Prentice, CRM 1983, 'Epoprostenol (prostacyclin) and severe arterial disease: a double-blind trial', Lancet, vol. 321, no. 8320, pp. 315-317. https://doi.org/10.1016/S0140-6736(83)91625-2

    Epoprostenol (prostacyclin) and severe arterial disease : a double-blind trial. / Belch, J. J. F.; McArdle, B.; Pollock, J. G.; Forbes, C. D.; Mckay, A.; Leiberman, P.; Lowe, G. D. O.; Prentice, C. R. M.

    In: Lancet, Vol. 321, No. 8320, 1983, p. 315-317.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Epoprostenol (prostacyclin) and severe arterial disease

    T2 - a double-blind trial

    AU - Belch, J. J. F.

    AU - McArdle, B.

    AU - Pollock, J. G.

    AU - Forbes, C. D.

    AU - Mckay, A.

    AU - Leiberman, P.

    AU - Lowe, G. D. O.

    AU - Prentice, C. R. M.

    N1 - Originally published as Volume 1, Issue 8320

    PY - 1983

    Y1 - 1983

    N2 - A 96 h infusion of epoprostenol (prostacyclin) or placebo was given as a treatment for rest pain to 28 patients with severe peripheral arterial disease. 24 h after the end of the infusion patients given epoprostenol had significantly less pain and took fewer analgesics tablets than did the controls. In some patients the epoprostenol effect lasted for over 1 month.

    AB - A 96 h infusion of epoprostenol (prostacyclin) or placebo was given as a treatment for rest pain to 28 patients with severe peripheral arterial disease. 24 h after the end of the infusion patients given epoprostenol had significantly less pain and took fewer analgesics tablets than did the controls. In some patients the epoprostenol effect lasted for over 1 month.

    U2 - 10.1016/S0140-6736(83)91625-2

    DO - 10.1016/S0140-6736(83)91625-2

    M3 - Article

    VL - 321

    SP - 315

    EP - 317

    JO - Lancet

    JF - Lancet

    SN - 0140-6736

    IS - 8320

    ER -

    Belch JJF, McArdle B, Pollock JG, Forbes CD, Mckay A, Leiberman P et al. Epoprostenol (prostacyclin) and severe arterial disease: a double-blind trial. Lancet. 1983;321(8320):315-317. https://doi.org/10.1016/S0140-6736(83)91625-2