Abstract
Autoinflammatory disorders (AID) are a heterogeneous group of diseases, characterized by an unprovoked innate immune response, resulting in recurrent or ongoing systemic inflammation and fever(1-3) . Inflammasomes are protein complexes with an essential role in pyroptosis and the caspase-1-mediated activation of the proinflammatory cytokines IL-1β, IL-17 and IL-18 (reviewed in(4,5) ). This article is protected by copyright. All rights reserved.
Original language | English |
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Pages (from-to) | 244-248 |
Number of pages | 5 |
Journal | British Journal of Dermatology |
Volume | 176 |
Issue number | 1 |
Early online date | 20 May 2016 |
DOIs | |
Publication status | Published - Jan 2017 |
Keywords
- NLRC4
- interleukin-18
- skin histology
- autosomal dominant
- Anakinra