Erythropoietin and spontaneous platelet aggregation in haemodialysis patients

J.E. Taylor, I.S. Henderson, W.K. Stewart, J.J.F. Belch

    Research output: Contribution to journalArticle

    57 Citations (Scopus)

    Abstract

    Erythropoietin significantly, reversibly, and reproducibly increased in-vitro whole-blood spontaneous platelet aggregation in 15 patients on haemodialysis. During erythropoietin treatment, spontaneous platelet aggregation was significantly higher in these subjects than in non-uraemic controls; concomitant treatment with 300 mg aspirin daily reversed platelet hyperaggregability. Erythropoietin may promote thrombosis by an effect on platelet function.
    Original languageEnglish
    Pages (from-to)1361-13622
    Number of pages2
    JournalLancet
    Volume338
    Issue number8779
    DOIs
    Publication statusPublished - 30 Nov 1991

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    Erythropoietin
    Renal Dialysis
    Blood Platelets
    Aspirin
    Thrombosis
    Therapeutics
    Spontaneous Platelet Aggregation

    Cite this

    Taylor, J.E. ; Henderson, I.S. ; Stewart, W.K. ; Belch, J.J.F. / Erythropoietin and spontaneous platelet aggregation in haemodialysis patients. In: Lancet. 1991 ; Vol. 338, No. 8779. pp. 1361-13622.
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    Erythropoietin and spontaneous platelet aggregation in haemodialysis patients. / Taylor, J.E.; Henderson, I.S.; Stewart, W.K.; Belch, J.J.F.

    In: Lancet, Vol. 338, No. 8779, 30.11.1991, p. 1361-13622.

    Research output: Contribution to journalArticle

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    AU - Taylor, J.E.

    AU - Henderson, I.S.

    AU - Stewart, W.K.

    AU - Belch, J.J.F.

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