Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

W.C. Earnshaw; R.C. Allshire; B.E. Black; K. Bloom; E.D. Salmon; B.R. Brinkley; W. Brown; I.M. Cheeseman; K.H.A. Choo; G.P. Copenhaver; J.G. DeLuca; K. Luger; A. Desai; K. Oegema; D.W. Cleveland; S. Diekmann; S. Erhardt; M. Fitzgerald-Hayes; D. Foltz; T. Fukagawa; R. Gassmann; H. Maiato; D.W. Gerlich; D.M. Glover; G.J. Gorbsky; S.C. Harrison; P. Heun; T. Hirota; L.E.T. Jansen; G. Karpen; G.J.P.L. Kops; M.A. Lampson; S.M. Lens; A. Losada; P.S. Maddox; R.L. Margolis; H. Masumoto; A.D. McAinsh; B.G. Mellone; R.J. O'Neill; P. Meraldi; A. Musacchio; K.C. Scott; B.A. Sullivan; A.F. Straight; P.T. Stukenberg; K.F. Sullivan; C.E. Sunkel; J.R. Swedlow; C.E. Walczak; P.E. Warburton; S. Westermann; H.F. Willard; L. Wordeman; M. Yanagida; T.J. Yen; K. Yoda

doi:10.1007/s10577-013-9347-y

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

W.C. Earnshaw
, R.C. Allshire
, B.E. Black
, K. Bloom
, E.D. Salmon
, B.R. Brinkley
, W. Brown
, I.M. Cheeseman
, K.H.A. Choo
, G.P. Copenhaver
, J.G. DeLuca
, K. Luger
, A. Desai
, K. Oegema
, D.W. Cleveland
, S. Diekmann
, S. Erhardt
, M. Fitzgerald-Hayes
, D. Foltz
, T. Fukagawa

R. Gassmann, H. Maiato, D.W. Gerlich, D.M. Glover, G.J. Gorbsky, S.C. Harrison, P. Heun, T. Hirota, L.E.T. Jansen, G. Karpen, G.J.P.L. Kops, M.A. Lampson, S.M. Lens, A. Losada, P.S. Maddox, R.L. Margolis, H. Masumoto, A.D. McAinsh, B.G. Mellone, R.J. O'Neill, P. Meraldi, A. Musacchio, K.C. Scott, B.A. Sullivan, A.F. Straight, P.T. Stukenberg, K.F. Sullivan, C.E. Sunkel, J.R. Swedlow, C.E. Walczak, P.E. Warburton, S. Westermann, H.F. Willard, L. Wordeman, M. Yanagida, T.J. Yen, K. Yoda

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.

Original language	English
Pages (from-to)	101-106
Number of pages	6
Journal	Chromosome Research
Volume	21
Issue number	2
DOIs	https://doi.org/10.1007/s10577-013-9347-y
Publication status	Published - 2013

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Earnshaw, W. C., Allshire, R. C., Black, B. E., Bloom, K., Salmon, E. D., Brinkley, B. R., Brown, W., Cheeseman, I. M., Choo, K. H. A., Copenhaver, G. P., DeLuca, J. G., Luger, K., Desai, A., Oegema, K., Cleveland, D. W., Diekmann, S., Erhardt, S., Fitzgerald-Hayes, M., Foltz, D., ... Yoda, K. (2013). Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research, 21(2), 101-106. https://doi.org/10.1007/s10577-013-9347-y

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title = "Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant",

abstract = "The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.",

author = "W.C. Earnshaw and R.C. Allshire and B.E. Black and K. Bloom and E.D. Salmon and B.R. Brinkley and W. Brown and I.M. Cheeseman and K.H.A. Choo and G.P. Copenhaver and J.G. DeLuca and K. Luger and A. Desai and K. Oegema and D.W. Cleveland and S. Diekmann and S. Erhardt and M. Fitzgerald-Hayes and D. Foltz and T. Fukagawa and R. Gassmann and H. Maiato and D.W. Gerlich and D.M. Glover and G.J. Gorbsky and S.C. Harrison and P. Heun and T. Hirota and L.E.T. Jansen and G. Karpen and G.J.P.L. Kops and M.A. Lampson and S.M. Lens and A. Losada and P.S. Maddox and R.L. Margolis and H. Masumoto and A.D. McAinsh and B.G. Mellone and R.J. O'Neill and P. Meraldi and A. Musacchio and K.C. Scott and B.A. Sullivan and A.F. Straight and P.T. Stukenberg and K.F. Sullivan and C.E. Sunkel and J.R. Swedlow and C.E. Walczak and P.E. Warburton and S. Westermann and H.F. Willard and L. Wordeman and M. Yanagida and T.J. Yen and K. Yoda",

year = "2013",

doi = "10.1007/s10577-013-9347-y",

language = "English",

volume = "21",

pages = "101--106",

journal = "Chromosome Research",

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Earnshaw, WC, Allshire, RC, Black, BE, Bloom, K, Salmon, ED, Brinkley, BR, Brown, W, Cheeseman, IM, Choo, KHA, Copenhaver, GP, DeLuca, JG, Luger, K, Desai, A, Oegema, K, Cleveland, DW, Diekmann, S, Erhardt, S, Fitzgerald-Hayes, M, Foltz, D, Fukagawa, T, Gassmann, R, Maiato, H, Gerlich, DW, Glover, DM, Gorbsky, GJ, Harrison, SC, Heun, P, Hirota, T, Jansen, LET, Karpen, G, Kops, GJPL, Lampson, MA, Lens, SM, Losada, A, Maddox, PS, Margolis, RL, Masumoto, H, McAinsh, AD, Mellone, BG, O'Neill, RJ, Meraldi, P, Musacchio, A, Scott, KC, Sullivan, BA, Straight, AF, Stukenberg, PT, Sullivan, KF, Sunkel, CE, Swedlow, JR, Walczak, CE, Warburton, PE, Westermann, S, Willard, HF, Wordeman, L, Yanagida, M, Yen, TJ & Yoda, K 2013, 'Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant', Chromosome Research, vol. 21, no. 2, pp. 101-106. https://doi.org/10.1007/s10577-013-9347-y

TY - JOUR

T1 - Esperanto for histones

T2 - CENP-A, not CenH3, is the centromeric histone H3 variant

AU - Earnshaw, W.C.

AU - Allshire, R.C.

AU - Black, B.E.

AU - Bloom, K.

AU - Salmon, E.D.

AU - Brinkley, B.R.

AU - Brown, W.

AU - Cheeseman, I.M.

AU - Choo, K.H.A.

AU - Copenhaver, G.P.

AU - DeLuca, J.G.

AU - Luger, K.

AU - Desai, A.

AU - Oegema, K.

AU - Cleveland, D.W.

AU - Diekmann, S.

AU - Erhardt, S.

AU - Fitzgerald-Hayes, M.

AU - Foltz, D.

AU - Fukagawa, T.

AU - Gassmann, R.

AU - Maiato, H.

AU - Gerlich, D.W.

AU - Glover, D.M.

AU - Gorbsky, G.J.

AU - Harrison, S.C.

AU - Heun, P.

AU - Hirota, T.

AU - Jansen, L.E.T.

AU - Karpen, G.

AU - Kops, G.J.P.L.

AU - Lampson, M.A.

AU - Lens, S.M.

AU - Losada, A.

AU - Maddox, P.S.

AU - Margolis, R.L.

AU - Masumoto, H.

AU - McAinsh, A.D.

AU - Mellone, B.G.

AU - O'Neill, R.J.

AU - Meraldi, P.

AU - Musacchio, A.

AU - Scott, K.C.

AU - Sullivan, B.A.

AU - Straight, A.F.

AU - Stukenberg, P.T.

AU - Sullivan, K.F.

AU - Sunkel, C.E.

AU - Swedlow, J.R.

AU - Walczak, C.E.

AU - Warburton, P.E.

AU - Westermann, S.

AU - Willard, H.F.

AU - Wordeman, L.

AU - Yanagida, M.

AU - Yen, T.J.

AU - Yoda, K.

PY - 2013

Y1 - 2013

N2 - The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.

AB - The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.

UR - https://www.scopus.com/pages/publications/84880573233

U2 - 10.1007/s10577-013-9347-y

DO - 10.1007/s10577-013-9347-y

M3 - Article

SN - 0967-3849

VL - 21

SP - 101

EP - 106

JO - Chromosome Research

JF - Chromosome Research

IS - 2

ER -

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

Abstract

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