European multicentre study to define disease activity criteria for systemic sclerosis. *I. clinical and epidemiological features of 290 patients from 19 centres

A. Della Rossa, G. Valentini, S. Bombardieri, W. Bencivelli, A. J. Silman, S. D'Angelo, M. Matucci Cerinic, J. F. Belch, C. M. Black, R. Becvar, P. Bruhlman, F. Cozzi, L. Czirják, A. A. Drosos, B. Dziankowska, C. Ferri, A. Gabrielli, R. Giacomelli, G. Hayem, M. InancN. J. McHugh, H. Nielsen, R. Scorza, E. Tirri, F. H. J. van den Hoogen, P. G. Vlachoyiannopoulos

    Research output: Contribution to journalArticle

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    Abstract

    Abstract
    Objective—To investigate the existence of differences among European referral centres for systemic sclerosis (SSc) in the pattern of attendance and referral and in the clinical and therapeutical approaches.
    Methods—In 1995 the European Scleroderma Study Group initiated a multicentre
    prospective one year study whose aim was to define the disease activity criteria
    in SSc. During the study period each participating European centre was asked to
    enrol consecutive patients satisfying American College of Rheumatology criteria
    for SSc and to fill out for each of them a standardised clinical chart. Patients
    from various centres were compared and differences in epidemiological, clinical,
    and therapeutical aspects were analysed.
    Results—Nineteen different medical research centres consecutively recruited 290
    patients. The patients could be divided into two subgroups: 173 with the limited
    (lSSc) and 117 with the diffuse (dSSc) form of the disease. The clinical and serological findings for the series of 290 patients seemed to be similar to data previously reported. However, when the data were analysed to elicit any differences between the participating centres, a high degree of variability emerged, in both epidemiological and clinical features and in the diagnostic and therapeutic approaches to the disease.
    Conclusions—The clinical approach to SSc, not only in different countries but
    also in different centres within the same country, is not yet standardised. To overcome this problem, it will be necessary for the scientific community to draw up a standardised procedure for the management of patients with SSc. This would provide a common research tool for different centres engaged in research on this complex disease.
    Original languageEnglish
    Pages (from-to)585-591
    Number of pages7
    JournalAnnals of the Rheumatic Diseases
    Volume60
    Issue number6
    DOIs
    Publication statusPublished - 2001

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    Systemic Scleroderma
    Multicenter Studies
    Referral and Consultation
    Research
    Biomedical Research

    Cite this

    Della Rossa, A., Valentini, G., Bombardieri, S., Bencivelli, W., Silman, A. J., D'Angelo, S., ... Vlachoyiannopoulos, P. G. (2001). European multicentre study to define disease activity criteria for systemic sclerosis. *I. clinical and epidemiological features of 290 patients from 19 centres. Annals of the Rheumatic Diseases, 60(6), 585-591. https://doi.org/10.1136/ard.60.6.585
    Della Rossa, A. ; Valentini, G. ; Bombardieri, S. ; Bencivelli, W. ; Silman, A. J. ; D'Angelo, S. ; Cerinic, M. Matucci ; Belch, J. F. ; Black, C. M. ; Becvar, R. ; Bruhlman, P. ; Cozzi, F. ; Czirják, L. ; Drosos, A. A. ; Dziankowska, B. ; Ferri, C. ; Gabrielli, A. ; Giacomelli, R. ; Hayem, G. ; Inanc, M. ; McHugh, N. J. ; Nielsen, H. ; Scorza, R. ; Tirri, E. ; van den Hoogen, F. H. J. ; Vlachoyiannopoulos, P. G. / European multicentre study to define disease activity criteria for systemic sclerosis. *I. clinical and epidemiological features of 290 patients from 19 centres. In: Annals of the Rheumatic Diseases. 2001 ; Vol. 60, No. 6. pp. 585-591.
    @article{ea5062c2b97f46beafeccadafc56c8e4,
    title = "European multicentre study to define disease activity criteria for systemic sclerosis. *I.: clinical and epidemiological features of 290 patients from 19 centres",
    abstract = "AbstractObjective—To investigate the existence of differences among European referral centres for systemic sclerosis (SSc) in the pattern of attendance and referral and in the clinical and therapeutical approaches.Methods—In 1995 the European Scleroderma Study Group initiated a multicentreprospective one year study whose aim was to define the disease activity criteriain SSc. During the study period each participating European centre was asked toenrol consecutive patients satisfying American College of Rheumatology criteriafor SSc and to fill out for each of them a standardised clinical chart. Patientsfrom various centres were compared and differences in epidemiological, clinical,and therapeutical aspects were analysed. Results—Nineteen different medical research centres consecutively recruited 290patients. The patients could be divided into two subgroups: 173 with the limited(lSSc) and 117 with the diffuse (dSSc) form of the disease. The clinical and serological findings for the series of 290 patients seemed to be similar to data previously reported. However, when the data were analysed to elicit any differences between the participating centres, a high degree of variability emerged, in both epidemiological and clinical features and in the diagnostic and therapeutic approaches to the disease.Conclusions—The clinical approach to SSc, not only in different countries butalso in different centres within the same country, is not yet standardised. To overcome this problem, it will be necessary for the scientific community to draw up a standardised procedure for the management of patients with SSc. This would provide a common research tool for different centres engaged in research on this complex disease.",
    author = "{Della Rossa}, A. and G. Valentini and S. Bombardieri and W. Bencivelli and Silman, {A. J.} and S. D'Angelo and Cerinic, {M. Matucci} and Belch, {J. F.} and Black, {C. M.} and R. Becvar and P. Bruhlman and F. Cozzi and L. Czirj{\'a}k and Drosos, {A. A.} and B. Dziankowska and C. Ferri and A. Gabrielli and R. Giacomelli and G. Hayem and M. Inanc and McHugh, {N. J.} and H. Nielsen and R. Scorza and E. Tirri and {van den Hoogen}, {F. H. J.} and Vlachoyiannopoulos, {P. G.}",
    year = "2001",
    doi = "10.1136/ard.60.6.585",
    language = "English",
    volume = "60",
    pages = "585--591",
    journal = "Annals of the Rheumatic Diseases",
    issn = "0003-4967",
    publisher = "BMJ Publishing Group",
    number = "6",

    }

    Della Rossa, A, Valentini, G, Bombardieri, S, Bencivelli, W, Silman, AJ, D'Angelo, S, Cerinic, MM, Belch, JF, Black, CM, Becvar, R, Bruhlman, P, Cozzi, F, Czirják, L, Drosos, AA, Dziankowska, B, Ferri, C, Gabrielli, A, Giacomelli, R, Hayem, G, Inanc, M, McHugh, NJ, Nielsen, H, Scorza, R, Tirri, E, van den Hoogen, FHJ & Vlachoyiannopoulos, PG 2001, 'European multicentre study to define disease activity criteria for systemic sclerosis. *I. clinical and epidemiological features of 290 patients from 19 centres', Annals of the Rheumatic Diseases, vol. 60, no. 6, pp. 585-591. https://doi.org/10.1136/ard.60.6.585

    European multicentre study to define disease activity criteria for systemic sclerosis. *I. clinical and epidemiological features of 290 patients from 19 centres. / Della Rossa, A.; Valentini, G.; Bombardieri, S.; Bencivelli, W.; Silman, A. J.; D'Angelo, S.; Cerinic, M. Matucci; Belch, J. F.; Black, C. M.; Becvar, R.; Bruhlman, P.; Cozzi, F.; Czirják, L.; Drosos, A. A.; Dziankowska, B.; Ferri, C.; Gabrielli, A.; Giacomelli, R.; Hayem, G.; Inanc, M.; McHugh, N. J.; Nielsen, H.; Scorza, R.; Tirri, E.; van den Hoogen, F. H. J.; Vlachoyiannopoulos, P. G.

    In: Annals of the Rheumatic Diseases, Vol. 60, No. 6, 2001, p. 585-591.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - European multicentre study to define disease activity criteria for systemic sclerosis. *I.

    T2 - clinical and epidemiological features of 290 patients from 19 centres

    AU - Della Rossa, A.

    AU - Valentini, G.

    AU - Bombardieri, S.

    AU - Bencivelli, W.

    AU - Silman, A. J.

    AU - D'Angelo, S.

    AU - Cerinic, M. Matucci

    AU - Belch, J. F.

    AU - Black, C. M.

    AU - Becvar, R.

    AU - Bruhlman, P.

    AU - Cozzi, F.

    AU - Czirják, L.

    AU - Drosos, A. A.

    AU - Dziankowska, B.

    AU - Ferri, C.

    AU - Gabrielli, A.

    AU - Giacomelli, R.

    AU - Hayem, G.

    AU - Inanc, M.

    AU - McHugh, N. J.

    AU - Nielsen, H.

    AU - Scorza, R.

    AU - Tirri, E.

    AU - van den Hoogen, F. H. J.

    AU - Vlachoyiannopoulos, P. G.

    PY - 2001

    Y1 - 2001

    N2 - AbstractObjective—To investigate the existence of differences among European referral centres for systemic sclerosis (SSc) in the pattern of attendance and referral and in the clinical and therapeutical approaches.Methods—In 1995 the European Scleroderma Study Group initiated a multicentreprospective one year study whose aim was to define the disease activity criteriain SSc. During the study period each participating European centre was asked toenrol consecutive patients satisfying American College of Rheumatology criteriafor SSc and to fill out for each of them a standardised clinical chart. Patientsfrom various centres were compared and differences in epidemiological, clinical,and therapeutical aspects were analysed. Results—Nineteen different medical research centres consecutively recruited 290patients. The patients could be divided into two subgroups: 173 with the limited(lSSc) and 117 with the diffuse (dSSc) form of the disease. The clinical and serological findings for the series of 290 patients seemed to be similar to data previously reported. However, when the data were analysed to elicit any differences between the participating centres, a high degree of variability emerged, in both epidemiological and clinical features and in the diagnostic and therapeutic approaches to the disease.Conclusions—The clinical approach to SSc, not only in different countries butalso in different centres within the same country, is not yet standardised. To overcome this problem, it will be necessary for the scientific community to draw up a standardised procedure for the management of patients with SSc. This would provide a common research tool for different centres engaged in research on this complex disease.

    AB - AbstractObjective—To investigate the existence of differences among European referral centres for systemic sclerosis (SSc) in the pattern of attendance and referral and in the clinical and therapeutical approaches.Methods—In 1995 the European Scleroderma Study Group initiated a multicentreprospective one year study whose aim was to define the disease activity criteriain SSc. During the study period each participating European centre was asked toenrol consecutive patients satisfying American College of Rheumatology criteriafor SSc and to fill out for each of them a standardised clinical chart. Patientsfrom various centres were compared and differences in epidemiological, clinical,and therapeutical aspects were analysed. Results—Nineteen different medical research centres consecutively recruited 290patients. The patients could be divided into two subgroups: 173 with the limited(lSSc) and 117 with the diffuse (dSSc) form of the disease. The clinical and serological findings for the series of 290 patients seemed to be similar to data previously reported. However, when the data were analysed to elicit any differences between the participating centres, a high degree of variability emerged, in both epidemiological and clinical features and in the diagnostic and therapeutic approaches to the disease.Conclusions—The clinical approach to SSc, not only in different countries butalso in different centres within the same country, is not yet standardised. To overcome this problem, it will be necessary for the scientific community to draw up a standardised procedure for the management of patients with SSc. This would provide a common research tool for different centres engaged in research on this complex disease.

    U2 - 10.1136/ard.60.6.585

    DO - 10.1136/ard.60.6.585

    M3 - Article

    C2 - 11350847

    VL - 60

    SP - 585

    EP - 591

    JO - Annals of the Rheumatic Diseases

    JF - Annals of the Rheumatic Diseases

    SN - 0003-4967

    IS - 6

    ER -