European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014

Daan Dittmar; Wolfgang Uter; Andrea Bauer; Anna B. Fortina; Andreas J. Bircher; Magdalena Czarnecka-Operacz; Aleksandra Dugonik; Peter Elsner; Rosella Gallo; Sharizan A. Ghaffar; Anna Giménez-Arnau; Graham A. Johnston; Beata Kręcisz; Francesca L. Filon; Thomas Rustemeyer; Anna Sadowska-Przytocka; Javier Sánchez-Pérez; Axel Schnuch; Dagmar Simon; Radoslaw Spiewak; Philipp Spring; Maria T. Corradin; Skaidra Valiukevičienė; Marko Vok; Elke Weisshaar; Mark Wilkinson; Marie L. Schuttelaar; for the ESSCA Network

doi:10.1111/cod.12966

European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014

Daan Dittmar
, Wolfgang Uter
, Andrea Bauer
, Anna B. Fortina
, Andreas J. Bircher
, Magdalena Czarnecka-Operacz
, Aleksandra Dugonik
, Peter Elsner
, Rosella Gallo
, Sharizan A. Ghaffar
, Anna Giménez-Arnau
, Graham A. Johnston
, Beata Kręcisz
, Francesca L. Filon
, Thomas Rustemeyer
, Anna Sadowska-Przytocka
, Javier Sánchez-Pérez
, Axel Schnuch
, Dagmar Simon
, Radoslaw Spiewak

Philipp Spring, Maria T. Corradin, Skaidra Valiukevičienė, Marko Vok, Elke Weisshaar, Mark Wilkinson, Marie L. Schuttelaar (Lead / Corresponding author), for the ESSCA Network

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Background: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life.

Objectives: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization.

Methods: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed.

Results: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization.

Conclusions: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.

Original language	English
Pages (from-to)	373-385
Number of pages	13
Journal	Contact Dermatitis
Volume	78
Issue number	6
Early online date	22 Feb 2018
DOIs	https://doi.org/10.1111/cod.12966
Publication status	Published - Jun 2018

Keywords

Journal article
Clinical epidemiology
Contact allergy
Patch test
Polysensitization
contact allergy
clinical epidemiology
patch test
polysensitization
Prevalence
Humans
Middle Aged
Patch Tests/statistics & numerical data
Dermatitis, Allergic Contact/epidemiology
Young Adult
Europe/epidemiology
Adult
Retrospective Studies
Allergens/immunology
Dermatitis, Atopic/epidemiology
Population Surveillance

ASJC Scopus subject areas

Dermatology
Immunology and Allergy

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10.1111/cod.12966

Cite this

Dittmar, D., Uter, W., Bauer, A., Fortina, A. B., Bircher, A. J., Czarnecka-Operacz, M., Dugonik, A., Elsner, P., Gallo, R., Ghaffar, S. A., Giménez-Arnau, A., Johnston, G. A., Kręcisz, B., Filon, F. L., Rustemeyer, T., Sadowska-Przytocka, A., Sánchez-Pérez, J., Schnuch, A., Simon, D., ... for the ESSCA Network (2018). European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014. Contact Dermatitis, 78(6), 373-385. https://doi.org/10.1111/cod.12966

@article{f048c4d3d38f4d6f90e93d8976af9f7d,

title = "European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014",

abstract = "Background: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life.Objectives: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization.Methods: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed.Results: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02\%, ranging from 12.7\% (Austria) to 4.6\% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization.Conclusions: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.",

keywords = "Journal article, Clinical epidemiology , Contact allergy, Patch test , Polysensitization, contact allergy, clinical epidemiology, patch test, polysensitization, Prevalence, Humans, Middle Aged, Patch Tests/statistics \& numerical data, Dermatitis, Allergic Contact/epidemiology, Young Adult, Europe/epidemiology, Adult, Retrospective Studies, Allergens/immunology, Dermatitis, Atopic/epidemiology, Population Surveillance",

author = "Daan Dittmar and Wolfgang Uter and Andrea Bauer and Fortina, \{Anna B.\} and Bircher, \{Andreas J.\} and Magdalena Czarnecka-Operacz and Aleksandra Dugonik and Peter Elsner and Rosella Gallo and Ghaffar, \{Sharizan A.\} and Anna Gim{\'e}nez-Arnau and Johnston, \{Graham A.\} and Beata Kr{\c e}cisz and Filon, \{Francesca L.\} and Thomas Rustemeyer and Anna Sadowska-Przytocka and Javier S{\'a}nchez-P{\'e}rez and Axel Schnuch and Dagmar Simon and Radoslaw Spiewak and Philipp Spring and Corradin, \{Maria T.\} and Skaidra Valiukevi{\v c}ienė and Marko Vok and Elke Weisshaar and Mark Wilkinson and Schuttelaar, \{Marie L.\} and \{for the ESSCA Network\}",

note = "The present study was not sponsored; the ESSCAhad received initial start-up funding from the EU(QLK4-CT-2001-00343 and QLK4-CT-2001-2812)in 2002–2004",

year = "2018",

month = jun,

doi = "10.1111/cod.12966",

language = "English",

volume = "78",

pages = "373--385",

journal = "Contact Dermatitis",

issn = "0105-1873",

publisher = "Wiley-Blackwell",

number = "6",

}

Dittmar, D, Uter, W, Bauer, A, Fortina, AB, Bircher, AJ, Czarnecka-Operacz, M, Dugonik, A, Elsner, P, Gallo, R, Ghaffar, SA, Giménez-Arnau, A, Johnston, GA, Kręcisz, B, Filon, FL, Rustemeyer, T, Sadowska-Przytocka, A, Sánchez-Pérez, J, Schnuch, A, Simon, D, Spiewak, R, Spring, P, Corradin, MT, Valiukevičienė, S, Vok, M, Weisshaar, E, Wilkinson, M, Schuttelaar, ML & for the ESSCA Network 2018, 'European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014', Contact Dermatitis, vol. 78, no. 6, pp. 373-385. https://doi.org/10.1111/cod.12966

TY - JOUR

T1 - European Surveillance System on Contact Allergies (ESSCA)

T2 - polysensitization, 2009-2014

AU - Dittmar, Daan

AU - Uter, Wolfgang

AU - Bauer, Andrea

AU - Fortina, Anna B.

AU - Bircher, Andreas J.

AU - Czarnecka-Operacz, Magdalena

AU - Dugonik, Aleksandra

AU - Elsner, Peter

AU - Gallo, Rosella

AU - Ghaffar, Sharizan A.

AU - Giménez-Arnau, Anna

AU - Johnston, Graham A.

AU - Kręcisz, Beata

AU - Filon, Francesca L.

AU - Rustemeyer, Thomas

AU - Sadowska-Przytocka, Anna

AU - Sánchez-Pérez, Javier

AU - Schnuch, Axel

AU - Simon, Dagmar

AU - Spiewak, Radoslaw

AU - Spring, Philipp

AU - Corradin, Maria T.

AU - Valiukevičienė, Skaidra

AU - Vok, Marko

AU - Weisshaar, Elke

AU - Wilkinson, Mark

AU - Schuttelaar, Marie L.

AU - for the ESSCA Network

N1 - The present study was not sponsored; the ESSCAhad received initial start-up funding from the EU(QLK4-CT-2001-00343 and QLK4-CT-2001-2812)in 2002–2004

PY - 2018/6

Y1 - 2018/6

N2 - Background: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life.Objectives: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization.Methods: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed.Results: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization.Conclusions: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.

AB - Background: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life.Objectives: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization.Methods: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed.Results: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization.Conclusions: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.

KW - Journal article

KW - Clinical epidemiology

KW - Contact allergy

KW - Patch test

KW - Polysensitization

KW - contact allergy

KW - clinical epidemiology

KW - patch test

KW - polysensitization

KW - Prevalence

KW - Humans

KW - Middle Aged

KW - Patch Tests/statistics & numerical data

KW - Dermatitis, Allergic Contact/epidemiology

KW - Young Adult

KW - Europe/epidemiology

KW - Adult

KW - Retrospective Studies

KW - Allergens/immunology

KW - Dermatitis, Atopic/epidemiology

KW - Population Surveillance

UR - https://www.scopus.com/pages/publications/85046374512

U2 - 10.1111/cod.12966

DO - 10.1111/cod.12966

M3 - Article

C2 - 29468728

SN - 0105-1873

VL - 78

SP - 373

EP - 385

JO - Contact Dermatitis

JF - Contact Dermatitis

IS - 6

ER -

European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014

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