Evaluation of a mobile-phone based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity

N. Kearney (Lead / Corresponding author), L. McCann, J. Norrie, L. Taylor, P. Gray, M. McGee-Lennon, M. Sage, M. Miller, R. Maguire

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    155 Citations (Scopus)

    Abstract

    To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS(A (c))) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer.

    A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial.

    Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals.

    One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy.

    A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS(A (c))).

    Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea).

    There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio = 2.29, 95%CI = 1.04 to 5.05, P = 0.040) and reports of hand-foot syndrome were on average lower in the control group (odds ratio control/intervention = 0.39, 95%CI = 0.17 to 0.92, P = 0.031).

    The study demonstrates that ASyMS(A (c)) can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.

    Original languageEnglish
    Pages (from-to)437-444
    Number of pages8
    JournalSupportive Care in Cancer
    Volume17
    Issue number4
    DOIs
    Publication statusPublished - 2009

    Keywords

    • Chemotherapy
    • Symptoms
    • Technology
    • Assessment

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