Evaluation of a mobile-phone based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity

TY - JOUR

T1 - Evaluation of a mobile-phone based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity

AU - Kearney, N.

AU - McCann, L.

AU - Norrie, J.

AU - Taylor, L.

AU - Gray, P.

AU - McGee-Lennon, M.

AU - Sage, M.

AU - Miller, M.

AU - Maguire, R.

PY - 2009

Y1 - 2009

N2 - To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS(A (c))) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer.A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial.Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals.One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy.A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS(A (c))).Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea).There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio = 2.29, 95%CI = 1.04 to 5.05, P = 0.040) and reports of hand-foot syndrome were on average lower in the control group (odds ratio control/intervention = 0.39, 95%CI = 0.17 to 0.92, P = 0.031).The study demonstrates that ASyMS(A (c)) can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.

AB - To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS(A (c))) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer.A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial.Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals.One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy.A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS(A (c))).Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea).There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio = 2.29, 95%CI = 1.04 to 5.05, P = 0.040) and reports of hand-foot syndrome were on average lower in the control group (odds ratio control/intervention = 0.39, 95%CI = 0.17 to 0.92, P = 0.031).The study demonstrates that ASyMS(A (c)) can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.

KW - Chemotherapy

KW - Symptoms

KW - Technology

KW - Assessment

U2 - 10.1007/s00520-008-0515-0

DO - 10.1007/s00520-008-0515-0

M3 - Article

SN - 0941-4355

VL - 17

SP - 437

EP - 444

JO - Supportive Care in Cancer

JF - Supportive Care in Cancer

IS - 4

ER -