Evidence-based sports supplements: A redox analysis

Nikos V Margaritelis; James N Cobley; George G Nastos; Konstantinos Papanikolaou; Stephen J Bailey; Paraskevi Kritsiligkou; Michalis G Nikolaidis

doi:10.1016/j.freeradbiomed.2024.08.012

Evidence-based sports supplements: A redox analysis

Nikos V Margaritelis (Lead / Corresponding author), James N Cobley, George G Nastos, Konstantinos Papanikolaou, Stephen J Bailey, Paraskevi Kritsiligkou, Michalis G Nikolaidis

Molecular Cell and Developmental Biology

Research output: Contribution to journal › Review article › peer-review

Abstract

Despite the overwhelming number of sports supplements on the market, only seven are currently recognized as effective. Biological functions are largely regulated through redox reactions, yet no comprehensive analysis of the redox properties of these supplements has been compiled. Here, we analyze the redox characteristics of these seven supplements: bicarbonates, beta-alanine, caffeine, creatine, nitrates, carbohydrates, and proteins. Our findings suggest that all sports supplements exhibit some degree of redox activity. However, the precise physiological implications of these redox properties remain unclear. Future research, employing unconventional perspectives and methodologies, will reveal new redox pixels of the exercise physiology and sports nutrition picture.

Original language	English
Pages (from-to)	62-77
Number of pages	16
Journal	Free Radical Biology and Medicine
Volume	224
Early online date	13 Aug 2024
DOIs	https://doi.org/10.1016/j.freeradbiomed.2024.08.012
Publication status	Published - 1 Nov 2024

Keywords

Antioxidants
Exercise
Oxidative stress
Signaling
Supplements

ASJC Scopus subject areas

Biochemistry
Physiology (medical)

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10.1016/j.freeradbiomed.2024.08.012

Cite this

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title = "Evidence-based sports supplements: A redox analysis",

abstract = "Despite the overwhelming number of sports supplements on the market, only seven are currently recognized as effective. Biological functions are largely regulated through redox reactions, yet no comprehensive analysis of the redox properties of these supplements has been compiled. Here, we analyze the redox characteristics of these seven supplements: bicarbonates, beta-alanine, caffeine, creatine, nitrates, carbohydrates, and proteins. Our findings suggest that all sports supplements exhibit some degree of redox activity. However, the precise physiological implications of these redox properties remain unclear. Future research, employing unconventional perspectives and methodologies, will reveal new redox pixels of the exercise physiology and sports nutrition picture.",

keywords = "Antioxidants, Exercise, Oxidative stress, Signaling, Supplements",

author = "Margaritelis, {Nikos V} and Cobley, {James N} and Nastos, {George G} and Konstantinos Papanikolaou and Bailey, {Stephen J} and Paraskevi Kritsiligkou and Nikolaidis, {Michalis G}",

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TY - JOUR

T1 - Evidence-based sports supplements

T2 - A redox analysis

AU - Margaritelis, Nikos V

AU - Cobley, James N

AU - Nastos, George G

AU - Papanikolaou, Konstantinos

AU - Bailey, Stephen J

AU - Kritsiligkou, Paraskevi

AU - Nikolaidis, Michalis G

PY - 2024/11/1

Y1 - 2024/11/1

N2 - Despite the overwhelming number of sports supplements on the market, only seven are currently recognized as effective. Biological functions are largely regulated through redox reactions, yet no comprehensive analysis of the redox properties of these supplements has been compiled. Here, we analyze the redox characteristics of these seven supplements: bicarbonates, beta-alanine, caffeine, creatine, nitrates, carbohydrates, and proteins. Our findings suggest that all sports supplements exhibit some degree of redox activity. However, the precise physiological implications of these redox properties remain unclear. Future research, employing unconventional perspectives and methodologies, will reveal new redox pixels of the exercise physiology and sports nutrition picture.

AB - Despite the overwhelming number of sports supplements on the market, only seven are currently recognized as effective. Biological functions are largely regulated through redox reactions, yet no comprehensive analysis of the redox properties of these supplements has been compiled. Here, we analyze the redox characteristics of these seven supplements: bicarbonates, beta-alanine, caffeine, creatine, nitrates, carbohydrates, and proteins. Our findings suggest that all sports supplements exhibit some degree of redox activity. However, the precise physiological implications of these redox properties remain unclear. Future research, employing unconventional perspectives and methodologies, will reveal new redox pixels of the exercise physiology and sports nutrition picture.

KW - Antioxidants

KW - Exercise

KW - Oxidative stress

KW - Signaling

KW - Supplements

U2 - 10.1016/j.freeradbiomed.2024.08.012

DO - 10.1016/j.freeradbiomed.2024.08.012

M3 - Review article

C2 - 39147071

SN - 0891-5849

VL - 224

SP - 62

EP - 77

JO - Free Radical Biology and Medicine

JF - Free Radical Biology and Medicine

ER -

Evidence-based sports supplements: A redox analysis

Abstract

Keywords

ASJC Scopus subject areas

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