Evolution of developmental cyclic adenosine monophosphate signaling in the Dictyostelia from an amoebozoan stress response

    Research output: Contribution to journalReview article

    13 Citations (Scopus)

    Abstract

    The Dictyostelid social amoebas represent one of nature's several inventions of multicellularity. Though normally feeding as single cells, nutrient stress triggers the collection of amoebas into colonies that form delicately shaped fruiting structures in which the cells differentiate into spores and up to three cell types to support the spore mass. Cyclic adenosine monophosphate (cAMP) plays a very dominant role in controlling morphogenesis and cell differentiation in the model species Dictyostelium discoideum. As a secreted chemoattractant cAMP coordinates cell movement during aggregation and fruiting body morphogenesis. Secreted cAMP also controls gene expression at different developmental stages, while intracellular cAMP is extensively used to transduce the effect of other stimuli that control the developmental program. In this review, I present an overview of the different roles of cAMP in the model D. discoideum and I summarize studies aimed to resolve how these roles emerged during Dictyostelid evolution.

    Original languageEnglish
    Pages (from-to)452-462
    Number of pages11
    JournalDevelopment, Growth & Differentiation
    Volume53
    Issue number4
    DOIs
    Publication statusPublished - May 2011

    Keywords

    • Amoebozoa
    • Cyclic adenosine monophosphate
    • Dictyostelium
    • Encystation
    • Evolution of multicellularity
    • Dependent protein kinase
    • Adenylyl-cyclase-G
    • Stalk cell differentiation
    • Terminal differentiation
    • Slime molds
    • Polysphondylium pallidum
    • CAMP receptor
    • Social amebas
    • Prespore differentiation
    • Sexual reproduction

    Cite this

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    title = "Evolution of developmental cyclic adenosine monophosphate signaling in the Dictyostelia from an amoebozoan stress response",
    abstract = "The Dictyostelid social amoebas represent one of nature's several inventions of multicellularity. Though normally feeding as single cells, nutrient stress triggers the collection of amoebas into colonies that form delicately shaped fruiting structures in which the cells differentiate into spores and up to three cell types to support the spore mass. Cyclic adenosine monophosphate (cAMP) plays a very dominant role in controlling morphogenesis and cell differentiation in the model species Dictyostelium discoideum. As a secreted chemoattractant cAMP coordinates cell movement during aggregation and fruiting body morphogenesis. Secreted cAMP also controls gene expression at different developmental stages, while intracellular cAMP is extensively used to transduce the effect of other stimuli that control the developmental program. In this review, I present an overview of the different roles of cAMP in the model D. discoideum and I summarize studies aimed to resolve how these roles emerged during Dictyostelid evolution.",
    keywords = "Amoebozoa, Cyclic adenosine monophosphate, Dictyostelium, Encystation, Evolution of multicellularity, Dependent protein kinase, Adenylyl-cyclase-G, Stalk cell differentiation, Terminal differentiation, Slime molds, Polysphondylium pallidum, CAMP receptor, Social amebas, Prespore differentiation, Sexual reproduction",
    author = "Pauline Schaap",
    year = "2011",
    month = "5",
    doi = "10.1111/j.1440-169X.2011.01263.x",
    language = "English",
    volume = "53",
    pages = "452--462",
    journal = "Development, Growth & Differentiation",
    issn = "0012-1592",
    publisher = "Wiley",
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    }

    TY - JOUR

    T1 - Evolution of developmental cyclic adenosine monophosphate signaling in the Dictyostelia from an amoebozoan stress response

    AU - Schaap, Pauline

    PY - 2011/5

    Y1 - 2011/5

    N2 - The Dictyostelid social amoebas represent one of nature's several inventions of multicellularity. Though normally feeding as single cells, nutrient stress triggers the collection of amoebas into colonies that form delicately shaped fruiting structures in which the cells differentiate into spores and up to three cell types to support the spore mass. Cyclic adenosine monophosphate (cAMP) plays a very dominant role in controlling morphogenesis and cell differentiation in the model species Dictyostelium discoideum. As a secreted chemoattractant cAMP coordinates cell movement during aggregation and fruiting body morphogenesis. Secreted cAMP also controls gene expression at different developmental stages, while intracellular cAMP is extensively used to transduce the effect of other stimuli that control the developmental program. In this review, I present an overview of the different roles of cAMP in the model D. discoideum and I summarize studies aimed to resolve how these roles emerged during Dictyostelid evolution.

    AB - The Dictyostelid social amoebas represent one of nature's several inventions of multicellularity. Though normally feeding as single cells, nutrient stress triggers the collection of amoebas into colonies that form delicately shaped fruiting structures in which the cells differentiate into spores and up to three cell types to support the spore mass. Cyclic adenosine monophosphate (cAMP) plays a very dominant role in controlling morphogenesis and cell differentiation in the model species Dictyostelium discoideum. As a secreted chemoattractant cAMP coordinates cell movement during aggregation and fruiting body morphogenesis. Secreted cAMP also controls gene expression at different developmental stages, while intracellular cAMP is extensively used to transduce the effect of other stimuli that control the developmental program. In this review, I present an overview of the different roles of cAMP in the model D. discoideum and I summarize studies aimed to resolve how these roles emerged during Dictyostelid evolution.

    KW - Amoebozoa

    KW - Cyclic adenosine monophosphate

    KW - Dictyostelium

    KW - Encystation

    KW - Evolution of multicellularity

    KW - Dependent protein kinase

    KW - Adenylyl-cyclase-G

    KW - Stalk cell differentiation

    KW - Terminal differentiation

    KW - Slime molds

    KW - Polysphondylium pallidum

    KW - CAMP receptor

    KW - Social amebas

    KW - Prespore differentiation

    KW - Sexual reproduction

    U2 - 10.1111/j.1440-169X.2011.01263.x

    DO - 10.1111/j.1440-169X.2011.01263.x

    M3 - Review article

    VL - 53

    SP - 452

    EP - 462

    JO - Development, Growth & Differentiation

    JF - Development, Growth & Differentiation

    SN - 0012-1592

    IS - 4

    ER -