TY - JOUR
T1 - Evolutionary aspects of GPI metabolism in kinetoplastid parasites
AU - Ferguson, Michael A. J.
AU - Masterson, Wayne J.
AU - Homans, Steve W.
AU - McConville, Malcolm J.
N1 - Medline is the source for the MeSH terms of this document.
PY - 1991
Y1 - 1991
N2 - There is a growing, but still very patchy, data base of GPI structure, biosynthesis and function. In this article we speculate freely on the function of GPI anchors, and the origins of GPI-related molecules, primarily with reference to the protozoan parasites Trypanosoma brucei and the Leishmania. The views expressed draw on fairly wild extrapolations and some will, no doubt, not stand the tests of time. Several of the hypotheses presented should therefore be taken with a pinch of salt, some lemon, and large quantities of tequila!
AB - There is a growing, but still very patchy, data base of GPI structure, biosynthesis and function. In this article we speculate freely on the function of GPI anchors, and the origins of GPI-related molecules, primarily with reference to the protozoan parasites Trypanosoma brucei and the Leishmania. The views expressed draw on fairly wild extrapolations and some will, no doubt, not stand the tests of time. Several of the hypotheses presented should therefore be taken with a pinch of salt, some lemon, and large quantities of tequila!
UR - http://www.scopus.com/inward/record.url?scp=0025999322&partnerID=8YFLogxK
U2 - 10.1016/0309-1651(91)90052-K
DO - 10.1016/0309-1651(91)90052-K
M3 - Article
AN - SCOPUS:0025999322
SN - 0309-1651
VL - 15
SP - 991
EP - 1005
JO - Cell Biology International Reports
JF - Cell Biology International Reports
IS - 11
ER -