Evolutionary origins and specialisation of membrane transport

Joel B. Dacks; Mark C. Field

doi:10.1016/j.ceb.2018.06.001

Evolutionary origins and specialisation of membrane transport

Joel B. Dacks, Mark C. Field (Lead / Corresponding author)

Biological Chemistry and Drug Discovery

Research output: Contribution to journal › Review article › peer-review

40 Citations (Scopus)

281 Downloads (Pure)

Abstract

From unicellular protists to the largest megafauna and flora, all eukaryotes depend upon the organelles and processes of the intracellular membrane trafficking system. Well-defined machinery selectively packages and delivers material between endomembrane organelles and imports and exports material from the cell surface. This process underlies intracellular compartmentalization and facilitates myriad processes that define eukaryotic biology. Membrane trafficking is a landmark in the origins of the eukaryotic cell and recent work has begun to unravel how the revolution in cellular structure occurred.

Original language	English
Pages (from-to)	70-76
Number of pages	7
Journal	Current Opinion in Cell Biology
Volume	53
Early online date	19 Jun 2018
DOIs	https://doi.org/10.1016/j.ceb.2018.06.001
Publication status	Published - 1 Aug 2018

ASJC Scopus subject areas

Cell Biology

Access to Document

10.1016/j.ceb.2018.06.001Licence: CC BY

Final Published VersionFinal published version, 626 KBLicence: CC BY

A Systems Approach for Understanding Cell Surface Dynamics in Trypanosomes (Investigator Award)
Field, M. (Investigator)
1/10/17 → 31/03/24
Project: Research
Global Mechanisms for Control of the Trypanosome Proteome: Defining the Composition, Origins and Roles of Cullin E3 Ligases
Field, M. (Investigator)
Medical Research Council
1/01/17 → 31/12/19
Project: Research
Control of Gene Expression in Trypanosoes: Defining the Nuclear Lamina
Field, M. (Investigator)
Medical Research Council
1/07/16 → 29/02/20
Project: Research

Cite this

@article{a8f134650fc14c7f833e0e41a588356a,

title = "Evolutionary origins and specialisation of membrane transport",

abstract = "From unicellular protists to the largest megafauna and flora, all eukaryotes depend upon the organelles and processes of the intracellular membrane trafficking system. Well-defined machinery selectively packages and delivers material between endomembrane organelles and imports and exports material from the cell surface. This process underlies intracellular compartmentalization and facilitates myriad processes that define eukaryotic biology. Membrane trafficking is a landmark in the origins of the eukaryotic cell and recent work has begun to unravel how the revolution in cellular structure occurred.",

author = "Dacks, {Joel B.} and Field, {Mark C.}",

note = "Work in the authors{\textquoteright} laboratories is supported by the Medical Research Council (MR/N010558/1 and MR/P009018/1 to MCF), the Wellcome Trust (204697/Z/16/ Z to MCF) and an NSERC Discovery grant (RES0021028 to JBD). JBD is the Canada Research Chair (Tier II) in Evolutionary Cell Biology. MCF is a Wellcome Trust Investigator.",

year = "2018",

month = aug,

day = "1",

doi = "10.1016/j.ceb.2018.06.001",

language = "English",

volume = "53",

pages = "70--76",

journal = "Current Opinion in Cell Biology",

issn = "0955-0674",

publisher = "Elsevier",

}

TY - JOUR

T1 - Evolutionary origins and specialisation of membrane transport

AU - Dacks, Joel B.

AU - Field, Mark C.

N1 - Work in the authors’ laboratories is supported by the Medical Research Council (MR/N010558/1 and MR/P009018/1 to MCF), the Wellcome Trust (204697/Z/16/ Z to MCF) and an NSERC Discovery grant (RES0021028 to JBD). JBD is the Canada Research Chair (Tier II) in Evolutionary Cell Biology. MCF is a Wellcome Trust Investigator.

PY - 2018/8/1

Y1 - 2018/8/1

N2 - From unicellular protists to the largest megafauna and flora, all eukaryotes depend upon the organelles and processes of the intracellular membrane trafficking system. Well-defined machinery selectively packages and delivers material between endomembrane organelles and imports and exports material from the cell surface. This process underlies intracellular compartmentalization and facilitates myriad processes that define eukaryotic biology. Membrane trafficking is a landmark in the origins of the eukaryotic cell and recent work has begun to unravel how the revolution in cellular structure occurred.

AB - From unicellular protists to the largest megafauna and flora, all eukaryotes depend upon the organelles and processes of the intracellular membrane trafficking system. Well-defined machinery selectively packages and delivers material between endomembrane organelles and imports and exports material from the cell surface. This process underlies intracellular compartmentalization and facilitates myriad processes that define eukaryotic biology. Membrane trafficking is a landmark in the origins of the eukaryotic cell and recent work has begun to unravel how the revolution in cellular structure occurred.

U2 - 10.1016/j.ceb.2018.06.001

DO - 10.1016/j.ceb.2018.06.001

M3 - Review article

C2 - 29929066

AN - SCOPUS:85048705428

SN - 0955-0674

VL - 53

SP - 70

EP - 76

JO - Current Opinion in Cell Biology

JF - Current Opinion in Cell Biology

ER -

Evolutionary origins and specialisation of membrane transport

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Projects

A Systems Approach for Understanding Cell Surface Dynamics in Trypanosomes (Investigator Award)

Global Mechanisms for Control of the Trypanosome Proteome: Defining the Composition, Origins and Roles of Cullin E3 Ligases

Control of Gene Expression in Trypanosoes: Defining the Nuclear Lamina

Cite this